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| Frank Yee, Ph.D. |
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Dr.
Frank Ye is an MRI physicist in the Functional
MRI Facility of the intramural research division in NIMH. Dr. Ye attended Beijing
University and obtained his B.Sc. and M.Sc. degrees there. He studied in University of Alberta and
obtained his Ph.D. in biomedical engineering in 1995. Dr. Ye did his postdoctoral research in the Brain
Disorders Branch in NIMH before he joined the Functional MRI Facility in 2001 as a staff scientist. |
| Research
Interests |
| Dr. Ye�s
primary responsibility is to provide instrumental and technical support in the fMRI study of non-human
primates on the newly purchased 4.7-Tesla vertical-bore MR monkey scanner. His expertise is in MRI
pulse sequence programming and experimental parameter optimization in fMRI protocols. His own
research interests have been in developing MRI techniques for reliable and accurate CBF measurement,
and in using combined perfusion and BOLD measurement to elucidate the physical and physiological
mechanisms underlying in-vivo fMRI techniques. |
| Representative
Selected Recent Publications: |
- F. Q. Ye, V. S. Mattay,
P. Jezzard, J. A. Frank, D. R. Weinberger and A. C.
McLaughlin (1997). Correction for vascular
artifacts in cerebral blood flow values measured using
arterial spin tagging techniques. Magn.
Reson. Med. 37: 226-235.
- F. Q. Ye, K. Faith
Berman, T. Ellmore, G. Esposito, J. D. van Horn, Y.
Yang, J. Duyn, A. M. Smith, J. A. Frank, D. R. Weinberger,
A. C. McLaughlin (2000). H2 15O PET validation
of steady-state arterial spin tagging cerebral blood
flow measurements in humans. Magn.
Reson. Med. 44:450-456.
- F. Q. Ye, J. A. Frank,
D. R. Weinberger, A. C. McLaughlin (2000).
Noise reduction in 3D perfusion imaging by attenuating
the static signal in arterial spin tagging (ASSIST).
Magn. Reson.
Med. 44:92-100.
- F. Q. Ye, A. M. Smith,
V. S. Mattay, U. Ruttiman, J. A. Frank, D. R. Weinberger,
A. C. McLaughlin (1998). Quantitation of regional
cerebral blood flow increase in the prefrontal cortex
during a working memory task: a steady-state arterial
spin tagging study. NeuroImage
8: 44-49.
- K. S. St Lawrence,
F. Q. Ye, B. K. Lewis, D. R. Weinberger, J. A. Frank,
A. C. McLaughlin (2002). Effects of indomethacin
on cerebral blood flow at rest and during hypercapnia:
an arterial spin tagging study in humans. J.
Magn. Reson. Imaging 15:628-635.
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| last updated 12/08/04 |
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