NIDA Research Monograph, Number 128 [Printed in 1992]
This monograph is not available by chapter. The Table of Contents (below) is shown to assist in locating information prior to downloading the monograph.
Download Monograph128.pdf - Statistical Issues in Clinical Trials for Treatment of Opiate Dependence (1.4 MB)
Table of Contents
Introduction-----1
Ram B. Jain
Drug Dependence (Addiction) and Its Treatment-----6
Frank J. Vocci, Jerome H. Jaffe, and Ram B. Jain
Background and Design of a Controlled Clinical Trial (ARC 090) for the Treatment of Opioid Dependence-----14
Rolley E. Johnson and Paul J. Fudala
Clinical Endpoints: Discussion Session-----25
Ram B. Jain
Design of Clinical Trials for Treatment of Opiate Dependence: What Is Missing?-----29
Ram B. Jain
Comments-----37
Sudhir C. Gupta
Rejoinder-----42
Ram B. Jain
Summary of Discussion-----44
Ram B. Jain
Efficacy of Urinalysis in Monitoring Heroin and Cocaine Abuse Patterns: Implications in Clinical Trials for Treatment of Drug Dependence-----46
Edward J. Cone and Sandra L. Dickerson
Comments-----59
Nancy L. Geller
Summary of Discussion-----62
Ram B. Jain
Open/Panel Discussion: Design Issues-----64
Ram B. Jain
A Bayesian Nonparametric Approach to Analysis of Treatment for
Drug Dependence Data-----70
Ram C. Tiwari
Three Estimators of the Probability of Opiate Use From Incomplete Data-----82
Alan J. Gross
Summary of Discussion-----95
Ram B. Jain
Issues in the Analysis of Clinical Trials for Opiate Dependence-----97
Dean Follmann, Margaret Wu, and Nancy Geller
Summary of Discussion-----114
Ram B. Jain
Analysis of Clinical Trials for Treatment of Opiate Dependence: What
Are the Possibilities?-----116
Ram B. Jain
Summary of Discussion-----135
Ram B. Jain
Toward a Dynamic Analysis of Disease-State Transition Monitored by
Serial Clinical Laboratory Tests-----137
T.S. Weng
Summary of Discussion-----158
Alan J. Gross
A Markov Model for NIDA Data on Treatment of Opiate Dependence-----160
Mei-Ling Ting Lee
Summary of Discussion-----168
Alan J. Gross
Open/Panel Discussion: Analysis Issues-----170
Ram B. Jain
Open/Panel Discussion: General Issues-----176
Ram B. Jain
List of Participants-----182
List of NIDA Research Monographs-----186
|
