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| Sponsored by: |
Department of Veterans Affairs |
|---|---|
| Information provided by: | Department of Veterans Affairs |
| ClinicalTrials.gov Identifier: | NCT00688259 |
Purpose
This is a study comparing the benefits of two types of individual psychotherapy (cognitive-behavioral therapy for psychosis and supportive therapy) in outpatients with schizophrenia or schizoaffective disorder. Treatmetn last 6 minths and ther are multiple assessment points.
| Condition | Intervention | Phase |
|---|---|---|
|
Schizophrenia Schizoaffective Disorder |
Other: supportive therapy Other: cognitive-behaioral therapy for psychosis |
Phase III |
| Study Type: | Interventional |
| Study Design: | Treatment, Randomized, Single Blind (Outcomes Assessor), Active Control, Factorial Assignment, Efficacy Study |
| Official Title: | Cognitive-Behavioral Therapy in Veterans With Schizophrenia |
| Estimated Enrollment: | 122 |
| Study Start Date: | October 2008 |
| Estimated Study Completion Date: | June 2012 |
| Estimated Primary Completion Date: | March 2012 (Final data collection date for primary outcome measure) |
| Arms | Assigned Interventions |
|---|---|
|
1: Experimental
approximately 20 sessions of individual manualized psychotherapy in which participants are taught to evaluate the data supporting beliefs that may interfere with recovery
|
Other: cognitive-behaioral therapy for psychosis
approximately 20 sessions of individual manualized psychotherapy in which participants are taught to evaluate the data supporting beliefs that may interfere with recovery
|
|
2: Active Comparator
approximately 20 sessions of manaulized psychotherapy to promote a strong alliance between the therapist and the participant in order to provide a safe place to discuss issues pertaining to recovery
|
Other: supportive therapy
approximately 20 sessions of manaulized psychotherapy to promote a strong alliance between the therapist and the participant in order to provide a safe palce to discuss issues pertaining to recovery
|
This is a randomized controlled trial comparing 6 months participation in one of two active treaments--cognitive-behavior therapy for psychosis and supportive therapy. Assessments of clinical status and social functioning will be obtained at baseline, mid-treatment, end of treatment, and 3 month follow-up. We hypothesize that participation in the cognitive-behaviorat therapy will lead to greater reductions in symptoms and improvements in social functioning.
Eligibility| Ages Eligible for Study: | 18 Years to 60 Years |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
Inclusion Criteria:
outpatients with schizophrenia or schizoaffectivd disorder in proximity to the west los angeles VAMC, at least one month since last hospitalization, stable antipsychotic medicaton for six months, persisting psychotic symptoms with at least minimal distress. competent to sign informed consent
Exclusion Criteria:
In other individual psychotherapy, presence of organic brain disease, mental retardation, or illness that would prohibit regular attendance in therapy. substance dependence diagnosis int he past 6 months,
Contacts and Locations| Contact: Shirley M Glynn, PhD | (310) 269-3939 | sglynn@ucla.edu |
| United States, California | |
| VA Greater Los Angeles Healthcare System, West LA | |
| West Los Angeles, California, United States, 90073 | |
| Principal Investigator: | Shirley M. Glynn, PhD | VA Greater Los Angeles Healthcare System, West LA |
More Information
| Responsible Party: | Department of Veterans Affairs ( Glynn, Shirley - Principal Investigator ) |
| Study ID Numbers: | MHBB-016-07S |
| Study First Received: | May 28, 2008 |
| Last Updated: | May 28, 2008 |
| ClinicalTrials.gov Identifier: | NCT00688259 |
| Health Authority: | United States: Federal Government |
|
clinical trials psychotherapy |
|
Schizophrenia Mental Disorders Psychotic Disorders Schizophrenia and Disorders with Psychotic Features |
