National Cancer Institute - U.S. National Institutes of Health - www.cancer.gov
National Cancer Institute - U.S. National Institutes of Health - www.cancer.gov

Clinical Trials by Cancer Site

Prostate Cancer

Prostate cancer is the most commonly diagnosed type of cancer in men and a disease that is frequently diagnosed in advanced stages due to the lack of symptoms in early-stage prostate cancer. There are several widely accepted risk factors, including age, ethnicity, and family history.

Prostate cancer is most frequently diagnosed in men 65 years of age or older. African American men have a higher incidence rate for prostate cancer than their counterparts. As with other types of cancers, family history may affect one's predisposition for the disease. Men at high risk of developing prostate cancer should begin screening for the disease at the age of 45. Common screening techniques include the PSA (prostate-specific antigen) test and the digital exam.

Treatment options for prostate cancer may vary depending on the patient's age, stage of disease, and other medical conditions, and should be discussed with the patient's physician.

Prostate Cancer Clinical Trials

The Center for Cancer Research (CCR), NCI's largest division doing research on campus, conducts prostate cancer clinical trials at the NIH Clinical Center in Bethesda, Md. NCI accepts referrals to prostate cancer clinical trials conducted in Bethesda, Md., through its Clinical Trials Referral Office (formerly called Clinical Studies Support Center)at 1-888-NCI-1937 (1-888-624-1937).

NCI is currently conducting the following trials for patients with prostate cancer. Click on the trials below for additional details, including a summary of eligibility criteria, treatment plan, and information on how to contact the principal investigators and their staff directly.


  
Trial and Protocol Number
Prostate Cancer
Phase II
A Phase II Study of Satraplatin and Prednisone in Metastatic Androgen-Independent Prostate Cancer (APIC)
NCI-08-C-0074

Principal Investigator:Referral Contact:
William L. DahutLaura D. Otten
301-435-8183301-451-1228
1-866-611-6310 (Toll Free)
ottenl@mail.nih.gov
A Double-Blind Randomized Phase 2.5 Trial of ONY-P1 Vaccine Versus Placebo in Men With D0 Prostate Cancer Following Limited Androgen Ablation
NCI-07-C-0188

Principal Investigator:Referral Contact:
James L. GulleyLaura D. Otten
301-435-2956301-451-1228
1-866-611-6310 (Toll Free)
ottenl@mail.nih.gov
A Randomized Phase II Trial Combining Vaccine Therapy With PROSTVAC/TRICOM and Flutamide vs. Flutamide Alone in Men With Androgen Insensitive, Non-Metastatic (D0.5) Prostate Cancer
NCI-07-C-0107

Principal Investigator:Referral Contact:
James L. GulleyLaura D. Otten
301-435-2956301-451-1228
1-866-611-6310 (Toll Free)
ottenl@mail.nih.gov
A Randomized Phase 2.5 Study of [153]Sm-EDTMP (Quadramet) With or Without a PSA TRICOM Vaccine in Men With Androgen-Insensitive Metastatic Prostate Cancer
NCI-07-C-0106

Principal Investigator:Referral Contact:
James L. GulleyLaura D. Otten
301-435-2956301-451-1228
1-866-611-6310 (Toll Free)
ottenl@mail.nih.gov
A Phase II Study of AZD2171 in Metastatic Androgen-Independent Prostate Cancer
NCI-07-C-0059

Principal Investigator:Referral Contact:
William L. DahutLaura D. Otten
301-435-8183301-451-1228
1-866-611-6310 (Toll Free)
ottenl@mail.nih.gov
Phase I
A Pilot Study of Image Guided Prostate and Pelvic Nodal Irradiation With Intensity Modulated Radiation Therapy (IMRT)
NCI-05-C-0241

Principal Investigator:Referral Contact:
Aradhana KaushalDeborah McNally
301-496-5457301-496-5457
cooleyd@navmed.nci.nih.gov
A Phase I Study of Image Guided Dose Escalation With Intensity Modulated Radiation Therapy (IMRT) to Histologically Confirmed Regions of Prostate Cancer
NCI-05-C-0191

Principal Investigator:Referral Contact:
Aradhana KaushalDeborah McNally
301-496-5457301-496-5457
cooleyd@navmed.nci.nih.gov
A Phase I Trial of High Dose Ketoconazole Plus Weekly Docetaxel in Metastatic Androgen Independent Prostate Cancer
NCI-02-C-0149

Principal Investigator:Referral Contact:
William L. DahutLaura D. Otten
301-435-8183301-451-1228
1-866-611-6310 (Toll Free)
ottenl@mail.nih.gov


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