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Summaries of Newsworthy Clinical Trial Results

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Hodgkin Lymphoma Trial Results
1.  PET Can Strongly Predict Likelihood of Early Relapse in Hodgkin Lymphoma
(Posted: 08/10/2007) - A positron emission tomography (PET) scan taken after two cycles of standard chemotherapy in patients with advanced Hodgkin lymphoma was able to predict with 92-percent accuracy how effective a complete course of the chemotherapy would be, according to a report published July 23, 2007 as an early release online publication of the August 20, 2007, issue of the Journal of Clinical Oncology.

2.  Lower-Toxicity Treatment Effective in Some Cases of Early-Stage Hodgkin's Lymphoma
(Posted: 07/10/2006) - An experimental low-intensity four-drug chemotherapy regimen plus limited radiation therapy improved cancer-free survival in patients with early-stage Hodgkin's lymphoma who had a favorable outlook, according to the July 1, 2006, issue of the Journal of Clinical Oncology.

3.  Palifermin Reduces Mouth Sores Caused by Blood Cancer Treatment
(Posted: 12/21/2004) - An experimental drug called palifermin (Kepivance®) reduced both the severity and the duration of sores and ulcers in the mouth in patients who received intensive chemotherapy and radiation to treat lymphoma and other cancers of the blood, according to a report in the Dec. 16, 2004, issue of the New England Journal of Medicine.

4.  No Added Benefit from Radiation for Hodgkin's Patients in Complete Remission
(Posted: 06/16/2003, Reviewed: 12/06/2005) - Radiation therapy offered no added benefit for patients with advanced Hodgkin’s lymphoma whose disease was in complete remission after multidrug chemotherapy, according to the June 12, 2003, New England Journal of Medicine.


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