Summaries & Associations of Study Results
| Levels of Evidence of Carcinogenicity | May Have Been Related | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TR | Chemical | Salmonella Results | Route | Male Rats | Female Rats | Male Mice | Female Mice | Sex/Species | Multiple Tumor Sites | |||
| TR-130 | Aniline hydrochloride | Dosed-Feed | P | (P) | N | N | Yes | |||||
| TR-154 | Azobenzene | +,+,+ | Dosed-Feed | (P) | (P) | N | N | No | ||||
| TR-189 | p-Chloroaniline | +,-,+W | Dosed-Feed | (E) | N | E | E | Yes | ||||
| TR-351 | p-Chloroaniline hydrochloride | Gavage | (CE) | (EE) | SE | NE | Yes | |||||
| TR-542 | Cumene | - | Inhalation | CE | SE | CE | CE | (MM) | Yes | |||
| TR-225 | D & C red no. 9 | +W | Dosed-Feed | (P) | E | N | N | Yes | ||||
| TR-360 | N,N-Dimethylaniline | - | Gavage | (SE) | NE | NE | EE | Yes | ||||
| TR-020 | 4,4'-Sulfonyldianiline (Dapsone) | - | Dosed-Feed | (P) | N | N | N | No | ||||
| TR-153 | o-Toluidine hydrochloride | +,- | Dosed-Feed | (P) | (P) | P | P | Yes | ||||
| TR-510 | Urethane | ?,+ | Dosed-Water | CE | (CE) | Yes | ||||||
| TR-510 | Urethane + ethanol (combination) | Dosed-Water | ||||||||||
| Totals | 7 | 4 | 1 | 1 | ||||||||
| The number of chemicals causing tumors in Spleen is 11. | ||||||||||||
Levels of Evidence of Carcinogenicity: CE or P = Clear Evidence, SE = Some Evidence, EE or E = Equivocal Evidence, NE or N = No Evidence, IS = Inadequate Experiment Salmonella Results: + = Positive, +W = Weakly Positive, ? = Inconclusive, - = Negative Parentheses indicate the animal group in which a tumor occurred in the organ specified. Sex/Species: MR = Male Rats, FR = Female Rats, MM = Male Mice, FM = Female Mice Totals include positive, equivocal and may-have-been-related responses where a tumor occurred in the organ specified. NOTE: Blank space under the animal groups indicates no experiments were done. | ||||||||||||
Web page last updated on May 14, 2008
