Summaries & Associations of Study Results
| Levels of Evidence of Carcinogenicity | May Have Been Related | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TR | Chemical | Salmonella Results | Route | Male Rats | Female Rats | Male Mice | Female Mice | Sex/Species | Multiple Tumor Sites | |||
| TR-289 | Benzene | - | Gavage | (CE) | (CE) | CE | CE | Yes | ||||
| TR-452 | 2,2-bis(Bromomethyl)-1,3-propanediol | +,+,- | Dosed-Feed | (CE) | (CE) | CE | CE | Yes | ||||
| TR-467 | Chloroprene | - | Inhalation | (CE) | (CE) | CE | CE | Yes | ||||
| TR-405 | C.I. Acid red 114 | + | Dosed-Water | CE | (CE) | (MR) | Yes | |||||
| TR-397 | C.I. Direct blue 15 | - | Dosed-Water | (CE) | (CE) | Yes | ||||||
| TR-430 | C.I. Direct blue 218 | - | Dosed-Feed | (SE) | NE | CE | CE | Yes | ||||
| TR-479 | Coconut oil acid diethanolamine condensate | - | Topical Application | NE | EE | CE | CE | (FR) | Yes | |||
| TR-463 | D & C yellow no. 11 | +W,? | Dosed-Feed | (SE) | SE | (FR) | Yes | |||||
| TR-206 | 1,2-Dibromo-3-chloropropane | + | Inhalation | (P) | (P) | P | P | Yes | ||||
| TR-400 | 2,3-Dibromo-1-propanol | + | Topical Application | (CE) | (CE) | CE | CE | Yes | ||||
| TR-372 | 3,3'-Dimethoxybenzidine dihydrochloride | Dosed-Water | (CE) | (CE) | Yes | |||||||
| TR-390 | 3,3'-Dimethylbenzidine dihydrochloride | + | Dosed-Water | (CE) | (CE) | Yes | ||||||
| TR-316 | Dimethylvinyl chloride (DMVC) | -,+ | Gavage | (CE) | (CE) | CE | CE | Yes | ||||
| TR-374 | Glycidol | +,+ | Gavage | CE | (CE) | CE | CE | Yes | ||||
| TR-509 | 2,4-Hexadienal | +,+ | Gavage | CE | CE | CE | CE | (MM) | Yes | |||
| TR-546 | Sodium dichromate dihydrate (VI) | + | Dosed-Water | (CE) | (CE) | CE | CE | Yes | ||||
| TR-530 | TEF evaluation (Binary mixture; PCB 126/PCB 153) | Gavage | (CE) | Yes | ||||||||
| TR-525 | TEF evaluation (PECDF (Pentachlorodibenzofuran)) | Gavage | (SE) | Yes | ||||||||
| TR-531 | Tef Evaluation (Pcb Mixture; Pcb 126/Pcb 118) | Gavage | (CE) | Yes | ||||||||
| TR-521 | TEF evaluation (TCDD) | Gavage | (CE) | Yes | ||||||||
| TR-520 | Toxic equivalency factor evaluation ((PCB 126) 3,3',4,4',5-pentachlorobiphenyl) | Gavage | (CE) | Yes | ||||||||
| TR-384 | 1,2,3-Trichloropropane | +,+ | Gavage | (CE) | (CE) | CE | (CE) | (MM) | Yes | |||
| Totals | 14 | 20 | 2 | 1 | ||||||||
| The number of chemicals causing tumors in Oral Cavity is 22. | ||||||||||||
Levels of Evidence of Carcinogenicity: CE or P = Clear Evidence, SE = Some Evidence, EE or E = Equivocal Evidence, NE or N = No Evidence, IS = Inadequate Experiment Salmonella Results: + = Positive, +W = Weakly Positive, ? = Inconclusive, - = Negative Parentheses indicate the animal group in which a tumor occurred in the organ specified. Sex/Species: MR = Male Rats, FR = Female Rats, MM = Male Mice, FM = Female Mice Totals include positive, equivocal and may-have-been-related responses where a tumor occurred in the organ specified. NOTE: Blank space under the animal groups indicates no experiments were done. | ||||||||||||
Web page last updated on May 14, 2008
