Study Results & Research Projects

Summaries & Associations of Study Results

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http://ntp.niehs.nih.gov/go/SA-23

Chemicals Associated with Site-Specific Tumor Induction in Heart
 Levels of Evidence of Carcinogenicity May Have Been Related
TRChemicalSalmonella ResultsRouteMale RatsFemale RatsMale MiceFemale MiceSex/SpeciesMultiple Tumor Sites
TR-059Estradiol mustard GavageNN(P)(P)    Yes
TR-060Phenesterin-,-GavageNP(P)(P)    Yes
TR-510Urethane?,+Dosed-Water  (CE)CE    Yes
TR-510Urethane + ethanol (combination) Dosed-Water         
 Totals0032 
The number of chemicals causing tumors in Heart is 4.

Levels of Evidence of Carcinogenicity: CE or P = Clear Evidence, SE = Some Evidence, EE or E = Equivocal Evidence, NE or N = No Evidence, IS = Inadequate Experiment

Salmonella Results: + = Positive, +W = Weakly Positive, ? = Inconclusive, - = Negative

Parentheses indicate the animal group in which a tumor occurred in the organ specified.

Sex/Species: MR = Male Rats, FR = Female Rats, MM = Male Mice, FM = Female Mice

Totals include positive, equivocal and may-have-been-related responses where a tumor occurred in the organ specified.

NOTE: Blank space under the animal groups indicates no experiments were done.