Summaries & Associations of Study Results
Levels of Evidence of Carcinogenicity | May Have Been Related | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
TR | Chemical | Salmonella Results | Route | Male Rats | Female Rats | Male Mice | Female Mice | Sex/Species | Multiple Tumor Sites | |||
TR-059 | Estradiol mustard | Gavage | N | N | (P) | (P) | Yes | |||||
TR-060 | Phenesterin | -,- | Gavage | N | P | (P) | (P) | Yes | ||||
TR-510 | Urethane | ?,+ | Dosed-Water | (CE) | CE | Yes | ||||||
TR-510 | Urethane + ethanol (combination) | Dosed-Water | ||||||||||
Totals | 0 | 0 | 3 | 2 | ||||||||
The number of chemicals causing tumors in Heart is 4. | ||||||||||||
Levels of Evidence of Carcinogenicity: CE or P = Clear Evidence, SE = Some Evidence, EE or E = Equivocal Evidence, NE or N = No Evidence, IS = Inadequate Experiment Salmonella Results: + = Positive, +W = Weakly Positive, ? = Inconclusive, - = Negative Parentheses indicate the animal group in which a tumor occurred in the organ specified. Sex/Species: MR = Male Rats, FR = Female Rats, MM = Male Mice, FM = Female Mice Totals include positive, equivocal and may-have-been-related responses where a tumor occurred in the organ specified. NOTE: Blank space under the animal groups indicates no experiments were done. |
Web page last updated on May 14, 2008