Biosketch

Dr. Beigel is an investigator with both the Critical Care Medicine Department at the NIH Clinical Center and the Clinical Research Section, Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases.

He came to NIH in 2000 as a fellow in the Critical Care Medicine Department. He has held his current Clinical Center position as a staff clinician since 2005. He also is an attending physician for the Infectious Disease Service. He was recently detailed to assist the World Health Organization and the Office of Global Affairs of the U.S. Department of Health and Human Services on influenza issues.

Dr Beigel received his undergraduate degree from University of Rochester and his medical degree from Medical College of Ohio. He then completed a residency in internal medicine at the University of Cincinnati College of Medicine and a fellowship in infectious diseases at Massachusetts General Hospital.

His research focuses on clinical protocols to study the pathogenesis and treatment of SARS (severe acute respiratory syndrome), influenza, and avian influenza. He is the principal investigator on multiple protocols evaluating the pathogenesis of and developing and testing novel therapeutics for emerging diseases, including avian influenza. For example, he is the principal investigator for a multicenter international protocol focused on Southeast Asia to evaluate the pathogenesis and treatment of severe influenza and avian influenza.

Honors and Awards

Alpha Omega Alpha (national medical honor society), elected 1994

Selected Publications

JOURNAL ARTICLES

Beigel JH and P Eichacker. Hydrocortisone and Fludrocortisone Improved 28-day Survival in Septic Shock and Adrenal Insufficiency. ACP Journal Club 2003; 138:44.

Beigel JH and P Eichacker. Hydrocortisone and Fludrocortisone Improved 28-day Survival in Septic Shock and Adrenal Insufficiency. ACP Journal Club 2003; 138:44.

Beigel JH. SARS as a Paradigm of Emerging Infections. Critical Connections 2004; 3-4

Maria L. Jison, Peter J. Munson, Jennifer J. Barb, Anthony F. Suffredini, Shefali Talwar, Carolea Logun, Nalini Raghavachari, John H. Beigel, James H. Shelhamer, Robert L. Danner, and Mark T. Gladwin. Blood Gene Expression Profiles Characterize the Oxidant, Hemolytic and Inflammatory Stress of Sickle Cell Disease. Blood 2004; 104:270-280

Beigel J. Interpreting Diagnostic Studies in SARS – Defining the Reference. Clinical Immunology 2004. Clin Immunol. 2004 Nov;113(2):117-8.

Beigel JH. The emerging utility of neopterin? Clin Immunol., 116, 2005, 1, pp. 1-2

Beigel JH, Farrar J, Han AM, Hayden FG, Hyer R, de Jong MD, Lochindarat S, Nguyen TK, Nguyen TH, Tran TH, Nicoll A, Touch S, Yuen KY; Writing Committee of the World Health Organization (WHO) Consultation on Human Influenza A/H5. Avian influenza A (H5N1) infection in humans. N Engl J Med. 2005 Sep 29;353(13):1374-85.

Schunemann HJ, Hill SR, Kakad M, Bellamy R, Uyeki TM, Hayden FG, Yazdanpanah Y, Beigel J, Chotpitayasunondh T, Del Mar C, Farrar J, Tran TH, Ozbay B, Sugaya N, Fukuda K, Shindo N, Stockman L, Vist GE, Croisier A, Nagjdaliyev A, Roth C, Thomson G, Zucker H, Oxman AD; WHO Rapid Advice Guideline Panel on Avian Influenza.

WHO Rapid Advice Guidelines for pharmacological management of sporadic human infection with avian influenza A (H5N1) virus. Lancet Infect Dis. 2007 Jan;7(1):21-31S