Functional Abilities in Rett Syndrome - Full Text View

Sponsors and Collaborators:	Faculdades Metropolitanas Unidas University of Sao Paulo
Information provided by:	Faculdades Metropolitanas Unidas
ClinicalTrials.gov Identifier:	NCT00630422

Purpose

The purpose of this study is to evaluate and determinate the functional abilities in Rett syndrome conforming to the established Pediatric Evaluation of Disability Inventory (PEDI).

Condition
Rett Syndrome

Genetics Home Reference related topics: familial encephalopathy with neuroserpin inclusion bodies L1 syndrome Rett syndrome

MedlinePlus related topics: Rett Syndrome

U.S. FDA Resources

Study Type:	Observational
Study Design:	Ecologic or Community, Cross-Sectional
Official Title:	Functional Abilities in Rett Syndrome

Further study details as provided by Faculdades Metropolitanas Unidas:

Biospecimen Retention: None Retained

Biospecimen Description:

Enrollment:	64
Study Start Date:	February 2006
Study Completion Date:	December 2006
Primary Completion Date:	September 2006 (Final data collection date for primary outcome measure)

Groups/Cohorts
64 All Patients

Detailed Description:

Rett syndrome (RS) is a progressive neurological disturbance of genetic cause that affects females almost exclusively. It is caused by mutations, usually sporadic, of the MECP2 gene located in the X chromosome. In consequence to the serious cognitive and motor compromise, the RS patients have great difficulty in accomplishing day-to-day tasks. The objective of this work is to evaluate the functional abilities in RS to help therapists in theirs treatments programs.

Eligibility

Genders Eligible for Study:	Female
Accepts Healthy Volunteers:	Yes
Sampling Method:	Probability Sample

Study Population

This study investigated only patients with Rett syndrome that matched the criteria for the classic form of the disease

Criteria

Inclusion Criteria:

Patients with Rett syndrome that matched the criteria for the classic form of the disease

Exclusion Criteria:

Any other disease;
Rett syndrome associated with other disease
Rett syndrome that not that matched the criteria for the classic form of the disease

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00630422

Locations

Brazil
Faculdades Metropolitanas Unidas
São Paulo, Brazil, 04505-001

Sponsors and Collaborators

Faculdades Metropolitanas Unidas

University of Sao Paulo

Investigators

Principal Investigator:

Carlos BM Monteiro, PhD

Faculdades Metropolitanas Unidas

More Information

alread published This link exits the ClinicalTrials.gov site

Responsible Party:	Faculdades Metropolitanas Unidas ( carlos bandeira de mello monteiro )
Study ID Numbers:	monteiro, monteiro1
Study First Received:	January 17, 2008
Last Updated:	March 6, 2008
ClinicalTrials.gov Identifier:	NCT00630422
Health Authority:	Brazil: National Committee of Ethics in Research

Keywords provided by Faculdades Metropolitanas Unidas:

Rett Syndrome
Selfcare
Mobility limitation
Interpersonal relations
This study avaliated patients with Rett Syndrome

Study placed in the following topic categories:

Mobility Limitation
Developmental Disabilities
Rett syndrome
Neurodegenerative Diseases
Mental Retardation
Child Development Disorders, Pervasive
Rett Syndrome

Heredodegenerative Disorders, Nervous System
Genetic Diseases, Inborn
Mental Disorders
Mental Disorders Diagnosed in Childhood
Genetic Diseases, X-Linked
Neurologic Manifestations
Neurobehavioral Manifestations

Additional relevant MeSH terms:

Pathologic Processes
Disease
Syndrome
Nervous System Diseases
Mental Retardation, X-Linked

ClinicalTrials.gov processed this record on January 15, 2009