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Cytomegalovirus Reactivation in Cancer Patients Receiving Chemotherapy
This study has been completed.
Sponsored by: Mackay Memorial Hospital
Information provided by: Mackay Memorial Hospital
ClinicalTrials.gov Identifier: NCT00366717
  Purpose

Cytomegalovirus (CMV) infects most of the world population. This study is to understand if chemotherapy will increase the chance of reactivating CMV. The results may help us in determining when treatment is needed and perhaps Why is it needed.


Condition
Cancer
Cytomegalovirus

MedlinePlus related topics: Cancer Cytomegalovirus Infections
U.S. FDA Resources
Study Type: Observational
Study Design: Screening, Longitudinal, Defined Population, Prospective Study

Further study details as provided by Mackay Memorial Hospital:

Estimated Enrollment: 20
Study Start Date: June 2005
Estimated Study Completion Date: January 2006
Detailed Description:

Despite CMV reactivation has been clearly described in patients underwent transplantation, this phenomenon has not been studied in patients undergoing chemotherapy. Our purpose is to understand if CMV number increases in monocytic leukocytes during chemotherapy and how is the host response to that changes.

Virus load will be studied by quantitative PCR, host response will be studied by measuring patient's anti-CMV IgG, CMV-associated symptoms, serum IFN-r and TNF-a.

  Eligibility

Ages Eligible for Study:   20 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • clinical diagnosis of any cancer
  • chemotherapy is needed for more than 6 months
  • age>20 years old

Exclusion Criteria:

  • those who do not agree to participate
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00366717

Locations
Taiwan
Mackay Memorial Hospital
Taipei, Taiwan, 10449
Sponsors and Collaborators
Mackay Memorial Hospital
Investigators
Principal Investigator: Yen-Ta Lu, MD, PhD. Mackay Memorial Hospital
  More Information

Home page of Mackay Memorial Hospital  This link exits the ClinicalTrials.gov site

Study ID Numbers: MMH-I-S-144
Study First Received: August 18, 2006
Last Updated: August 18, 2006
ClinicalTrials.gov Identifier: NCT00366717  
Health Authority: Taiwan: Department of Health

Keywords provided by Mackay Memorial Hospital:
Cancer under chemotherapy

Study placed in the following topic categories:
Virus Diseases
Cytomegalovirus Infections
DNA Virus Infections
Cytomegalic inclusion disease
Cytomegalovirus
Herpesviridae Infections

ClinicalTrials.gov processed this record on January 16, 2009