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Sponsored by: |
The University of North Carolina, Chapel Hill |
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Information provided by: | The University of North Carolina, Chapel Hill |
ClinicalTrials.gov Identifier: | NCT00609414 |
This is a study of why and how physicians use albumin during the first 72 hours after a burn injury.
Condition |
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Burns |
Study Type: | Observational |
Study Design: | Prospective |
Official Title: | Albumin Use in Burn Patients |
Estimated Enrollment: | 500 |
Study Start Date: | January 2005 |
Estimated Study Completion Date: | December 2008 |
Primary Completion Date: | October 2008 (Final data collection date for primary outcome measure) |
While albumin has been a part of burn resuscitation for many years, its use remains varied and controversial. The purpose of this study is to describe the current practices of albumin administration during the first 72 hours after a burn injury. Participating sites will collect data on patients with at least a 20% Total Body Surface Area (TBSA) burn. Information will be recorded on type and extent of burn injury, basic demographic data, co-morbidities, outcomes and, for the first 72 hours post injury, if albumin was used and why, amount of resuscitation fluids and urine output, and use of vasopressors and diuretics.
Each participating site will retrospectively review 20 charts of consecutive admissions with at least a 20% TBSA burn. In addition, each site will collect data prospectively on 20 more patients with 20% TBSA burns. Prospective data is requested in order to capture as close as possible to "real time" the reasons physicians choose to give albumin. No Protected Health Information (PHI) will be recorded.
Data will be anlayzed for patterns of albumin use and reasons for albumin administration.
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Sampling Method: | Non-Probability Sample |
Patients who have 20% and greater Total Body Surface Area burns who received fluid resuscitation for these injuries.
Inclusion Criteria:
Exclusion Criteria:
United States, Arizona | |
Arizona Burn Center, Maricopa Medical Center | |
Phoenix, Arizona, United States, 85008 | |
United States, California | |
Bothin Burn Center, Saint Francis Memorial Hospital | |
San Francisco, California, United States, 94109 | |
United States, Florida | |
Shands at the University of Florida Burn Center | |
Gainesville, Florida, United States, 32610 | |
United States, Georgia | |
Joseph M Still Research Foundation Inc and Doctors Hospital of Augusta | |
Augusta, Georgia, United States, 30909 | |
United States, Kansas | |
Bothin Burn Center, University of Kansas Hospital | |
Kansas City, Kansas, United States, 66160 | |
United States, Minnesota | |
Regions Hospital Burn Center | |
St. Paul, Minnesota, United States, 55101 | |
United States, North Carolina | |
North Carolina Jaycee Burn Center, University of North Carolina Hospitals | |
Chapel Hill, North Carolina, United States, 27514 | |
United States, Ohio | |
Paul and Carol David Foundation Burn Institute, Akron Children's Hospital | |
Akron, Ohio, United States, 44308 | |
Shriners Hospitals for Children | |
Cincinnati, Ohio, United States, 45229 | |
United States, Oregon | |
Oregon Burn Center, Legacy Health System | |
Portland, Oregon, United States, 97227 | |
United States, Utah | |
University of Utah Hospitals Burn Center | |
Salt Lake City, Utah, United States, 84132 | |
Canada, Ontario | |
Ross Tilley Burn Centre, Sunnybrook Health Sciences Centre | |
Toronto, Ontario, Canada, M4N 3M5 |
Principal Investigator: | Bruce A. Cairns, MD | North Carolina Jaycee Burn Center, University of North Carolina Hospitals |
Responsible Party: | Department of Surgery, University of North Carolina at Chapel Hill ( Bruce A. Cairns MD ) |
Study ID Numbers: | 04-1392 |
Study First Received: | January 24, 2008 |
Last Updated: | October 15, 2008 |
ClinicalTrials.gov Identifier: | NCT00609414 |
Health Authority: | United States: Institutional Review Board |
Burns Albumin Fluid Resuscitation |
Burns Wounds and Injuries Disorders of Environmental Origin |