Antioxidant Treatment of Type 2 Diabetes

This study is not yet open for participant recruitment.

Verified by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), July 2008

Sponsored by:	National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Information provided by:	National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
ClinicalTrials.gov Identifier:	NCT00609102

Purpose

This study examines whether an antioxidant taken orally will improve glucose tolerance and insulin secretion in type 2 diabetic subjects.

Condition	Intervention	Phase
Type 2 Diabetes	Drug: Placebo Drug: n-aceylcysteine	Phase 0

MedlinePlus related topics: Antioxidants Diabetes

Study Type:	Interventional
Study Design:	Treatment, Randomized, Single Blind (Subject), Single Group Assignment

Further study details as provided by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK):

Primary Outcome Measures:

Secondary Outcome Measures:

Estimated Enrollment:	90
Study Start Date:	July 2008
Estimated Primary Completion Date:	July 2011 (Final data collection date for primary outcome measure)

Arms	Assigned Interventions
Placebo: Placebo Comparator	Drug: Placebo one capsule BID
antioxidant drug: Active Comparator n-acetylcysteine	Drug: n-aceylcysteine 450 mgm BID

Eligibility

Criteria

Inclusion Criteria: Subjects with a known diagnosis of type 2 diabetes -

Exclusion Criteria: None, except known intolerance to n-acetylcysteine

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00609102

Contacts

Contact: R Paul Robertson, MD

206-726-1210

Locations

United States, Washington
Pacific Northwest Research Institute
Seattle, Washington, United States, 98122

Sponsors and Collaborators

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

More Information

Responsible Party:	Pacific Northwest Research Institute ( R. Paul Robertson )
Study ID Numbers:	Antioxidant trmt type 2, NIH R01 38325-19
Study First Received:	January 23, 2008
Last Updated:	July 11, 2008
ClinicalTrials.gov Identifier:	NCT00609102
Health Authority:	United States: Federal Government

Keywords provided by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK):

Type 2 diabetes

Study placed in the following topic categories:

Metabolic Diseases
Diabetes Mellitus, Type 2
Diabetes Mellitus
Endocrine System Diseases

Endocrinopathy
Metabolic disorder
Glucose Metabolism Disorders

ClinicalTrials.gov processed this record on January 16, 2009