Spontaneous Rhythmic Activity in Spinal Motor Circuit Formation |
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| Air date: | Monday, March 26, 2007, 12:00:00 PM |
| Category: | Neuroscience |
| Runtime: | 75 minutes |
| NLM Title: | Spontaneous rhythmic activity in spinal motor circuit formation [electronic resource] / Lynn Landmesser. |
| Author: | Landmesser, Lynn T. National Institutes of Health (U.S.) |
| Publisher: | [Bethesda, Md. : National Institutes of Health, 2007] |
| Abstract: | (CIT): Dr. Landmesser will present her research aimed at understanding the role that spontaneous electrical activity plays in the development of spinal cord motor circuits and neuromuscular maturation, and to elucidate the cellular mechanisms that produce such activity. Her laboratory found that such activity occurs during axon outgrowth and that it is required for accurate pathfinding. Unlike mature circuits which are driven by glutamate, early spontaneous activity in both chick and mouse require both cholinergic and GABAergic/glycinergic transmission as well as electrical coupling. By working out in more detail the circuit that produces spontaneous activity in wild type mice, her laboratory can now make use of various transgenic mice in which subpopulations of neurons are genetically deleted or altered. NIH Neuroscience Seminar Series. |
| Subjects: | Motor Neurons--physiology Neural Pathways--embryology Neural Pathways--physiology Spinal Cord--embryology Spinal Cord--physiology |
| Publication Types: | Government Publications Lectures |
| Download: | Download
Video How to download a Videocast |
| NLM Classification: | WL 400 |
| NLM ID: | 101303659 |
| CIT File ID: | 13714 |
| CIT Live ID: | 5238 |
| Permanent link: | http://videocast.nih.gov/launch.asp?13714 |
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| Description | Runtime | Description | Runtime | |||
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Enhanced Audio Podcast | 1:11:55 |
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Enhanced Video Podcast | 1:11:55 | |