Last Update: 06/05/2008 Printer Friendly Printer Friendly   Email This Page Email This Page  

Multiple Hypothesis Testing

Principal investigator: James F. Troendle, Ph.D.
Research has focused primarily on simultaneous testing for differences in two groups on each of several outcome variables. Permutation and bootstrap methods for discrete outcomes have been developed that control the familywise error rate. Methods for normal outcomes have been developed to control the false discovery rate. Permutation methods that control the false discovery proportion or the number of false discoveries have been developed. Methodology for testing multiple Bernoulli outcomes while adjusting for covariates and controlling the familywise error rate has also been developed.
 
Selected Publications

Troendle JF. (2005). Multiple comparisons between two groups on multiple Bernoulli outcomes while accounting for covariates. Statistics in Medicine, 24:3581-3591. [Abstract]

Korn EL, Troendle JF, McShane LM, & Simon R. (2004). Controlling the number of false discoveries: Application to high-dimensional genomic data. Journal of Statistical Planning and Inference, 124:379-398.

Troendle JF. (2000). Stepwise normal theory multiple test procedures controlling the false discovery rate. Journal of Statistical Planning and Inference, 84:139-158.

 
For More Information:
News Releases
Publications/Materials
Research Resources
Contact Information:
Dr Germaine M Louis
Senior Investigator
Address:
6100 Executive Blvd Room 7B03, MSC 7510
Rockville, MD 20852
For FedEx use:
Rockville Md 20852
Phone: 301-496-6155
Fax: 301-402-2084
E-mail:
louisg@mail.nih.gov