![]() |
Home
Search
Study Topics
Glossary
|
![]() |
![]() |
![]() |
|
![]() |
|
![]() |
|
![]() |
|
![]() |
![]() |
![]() |
|
![]() |
Sponsored by: |
Sanofi-Aventis |
---|---|
Information provided by: | Sanofi-Aventis |
ClinicalTrials.gov Identifier: | NCT00637455 |
To compare the effects of fexofenadine HCl 180 mg, cetirizine 10 mg, and placebo on computerized scores derived from the Aeromedical Vigilance Task (AVT), a computerized objective measure of attention, accuracy and reaction time in healthy naval flight personnel. Specifically, the primary objective is to compare the AVT overall (average of the 18 blocks) mean change from baseline in total number of errors (commission errors + omission errors) between fexofenadine HCl and cetirizine 10 mg. Safety of these single-dose treatments also will be assessed.
Condition | Intervention | Phase |
---|---|---|
Seasonal Allergic Rhinitis |
Drug: fexofenadine HCl |
Phase IV |
Study Type: | Interventional |
Study Design: | Treatment, Randomized, Double-Blind, Crossover Assignment, Safety/Efficacy Study |
Official Title: | Single Center, Randomized,Double-Blind,Crossover Study Comparing the Effects of Single-Dose Fexofenadine HCl 180 mg, Cetirizine 10 mg, and Placebo on Cognitive Performance in Naval Flight Personnel |
Enrollment: | 72 |
Study Start Date: | September 2003 |
Study Completion Date: | January 2005 |
Ages Eligible for Study: | 18 Years and older |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | Yes |
Inclusion Criteria:
Exclusion Criteria:
Responsible Party: | sanofi-aventis ( Study Director ) |
Study ID Numbers: | MO16455A/4139 |
Study First Received: | March 10, 2008 |
Last Updated: | March 17, 2008 |
ClinicalTrials.gov Identifier: | NCT00637455 |
Health Authority: | United States: Institutional Review Board |
Otorhinolaryngologic Diseases Rhinitis Cetirizine Histamine Hypersensitivity Terfenadine Respiratory Tract Diseases |
Respiratory Tract Infections Rhinitis, Allergic, Seasonal Fexofenadine Hypersensitivity, Immediate Histamine phosphate Respiratory Hypersensitivity |
Neurotransmitter Agents Molecular Mechanisms of Pharmacological Action Histamine Antagonists Immune System Diseases Therapeutic Uses Physiological Effects of Drugs |
Histamine Agents Histamine H1 Antagonists Anti-Allergic Agents Histamine H1 Antagonists, Non-Sedating Pharmacologic Actions Nose Diseases |