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Innovations
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| Fast-track Cloning
Jennifer F. Medlin Abstract
 Until now, scientists who wanted to isolate and clone a gene or chromosomal fragment had to endure months of tedious analysis, sorting through a library of millions of fragments to find the exact ones they desired, then proceed through laborious and time-consuming mapping studies. And even though most of the chromosomal DNA has been cloned, until recently no one had directly isolated genes that correspond to specific diseases, nor had anyone directly isolated specific chromosomal regions from genomic DNA. It is expected that this discovery will allow other scientists to fill in knowledge gaps in the genome more quickly and accurately than ever before. Eric Green, chief of the genome technology branch of the National Human Genome Research Institute, compares the human genome to an immense book that contains the entire human genetic blueprint: "If you know a few words on page 48 and a few words on page 50, then [this method is] a reliable method to find out what's on page 49," he says.
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