Skin Imaging With Technologies in Development - Full Text View

Sponsors and Collaborators:	University of California, Irvine Beckman Laser Institute University of California Irvine
Information provided by:	University of California, Irvine
ClinicalTrials.gov Identifier:	NCT00764920

Purpose

The purpose of this research study is to develop new methods of looking at the human skin by using several devices. Each device has its own method of taking images of the skin. The data from these devices will be compared and analyzed.

Condition
Healthy

U.S. FDA Resources

Study Type:	Observational
Official Title:	Non-Invasive Imaging Modalities for Assessment of Normal and Lesional Skin

Further study details as provided by University of California, Irvine:

Primary Outcome Measures:

Learn information about the human skin which could be useful for diagnosis or guiding treatment. [ Time Frame: 4 weeks ] [ Designated as safety issue: Yes ]

Biospecimen Retention: None Retained

Biospecimen Description:

Estimated Enrollment:	500
Study Start Date:	October 2008
Estimated Study Completion Date:	October 2012
Estimated Primary Completion Date:	October 2012 (Final data collection date for primary outcome measure)

Groups/Cohorts
skin inaging

Detailed Description:

The devices being studied are:

Laser Speckle Imaging (LSI): LSI provides information about relative blood flow in a tissue. In skin it can be used to determine what areas have more blood flow and whether a particular intervention or treatment affects blood flow.
Optical Coherence Tomography (OCT) and Optical Doppler Tomography (ODT): OCT and ODT can provide pictures of blood vessels in an area of the body and can also tell how fast blood is flowing in that area.
Photon Migration Spectroscopy (PMS): PMS can provide information about the amount of blood, oxygen, fat and water is in a tissue.
Multi-Spectral Imaging (MI): MI allows operators to get a 3 dimensional image of structures within the skin but under the skin surface. This might help with diagnosis.
Multiphoton Microscopy (MPM) MPM also allows imaging of structures within the skin but under the surface.
Surface Enhanced Resonance Raman Spectroscopy (SERRS): SERRS can be used to determine the chemical components of structures within tissue.

Eligibility

Ages Eligible for Study:	18 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	Yes
Sampling Method:	Non-Probability Sample

Study Population

community sample

Criteria

Inclusion Criteria:

adult male or female 18 years of age or older

Exclusion Criteria:

Younger than 18 years old
pregnant woman

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00764920

Locations

United States, California
Beckman Laser Institute Medical clinic
Irvine, California, United States, 92612

Sponsors and Collaborators

University of California, Irvine

Beckman Laser Institute University of California Irvine

Investigators

Principal Investigator:

Kristen M Kelly, MD

Beckman Laser Institute University of California Irvine

More Information

Responsible Party:	Beckman Laser Institute ( Kristen Kelly )
Study ID Numbers:	LAMMP-30139, P41-RR01192
Study First Received:	September 30, 2008
Last Updated:	October 1, 2008
ClinicalTrials.gov Identifier:	NCT00764920
Health Authority:	United States: Institutional Review Board

Keywords provided by University of California, Irvine:

human skin

Study placed in the following topic categories:

Healthy

ClinicalTrials.gov processed this record on January 13, 2009