NCRR Grantee Wins Presidential Award

NCRR Grantee Wins Presidential Early Career Award for Scientists and Engineers

Dr. Jay Hove, an NCRR grantee at the University of Cincinnati, is one of 12 NIH-supported scientists to receive the nation's highest honor at the outset of his scientific career. NIH STATEMENT

Nominated by NCRR's Division of Comparative Medicine for the award, Hove's innovative research through the years has combined advances in optics, engineering, and biomedicine to describe—for the first time—the dynamic flow interactions that occur in both sick and healthy animal models.

In 2006, the NCRR provided Hove with $1.53 million to build upon these innovations. With this funding, Hove plans to create a state-of-the-art, cross-platform technology for 4-D imaging (3-D, plus real time) that would study how fluids, such as blood, flow in the zebrafish, a widely-used biomedical animal research model. RESEARCH ABSTRACT

Photo: Jay Hove, Ph.D., is using a high-tech "treadmill" to study spontaneous physical activity levels of zebrafish. By monitoring their movement and metabolic rates, he hopes to better understand how "fidgeting" affects caloric balance and which molecules may control that process. (University of Cincinnati Photo) HIGH-RESOLUTION IMAGE

Research in blood flow has a direct impact on our improved understanding and management of human health. Measuring blood flow gives researchers insight into oxygen and nutrient concentrations in blood. Such concentration measures are an indication of general cell health and may shed light on a wide-variety of diseases.

Through Hove's innovative approach of combining biomedical and fluid engineering tools, he and his colleagues are creating a unique "imaging toolbox" with which to understand a powerful new animal model of human disease. NCRR support of innovative research, such as Hove's, continues to accelerate the research discovery process and harnesses the power of shared resources to improve human health.

NCRR's Division of Comparative Medicine helps meet the needs of biomedical researchers for high-quality, disease-free animals and specialized animal research facilities. The Division supports both individuals and research organizations.

UNIVERSITY OF CINCINNATI NEWS RELEASE