The Longevity Genes in Founder Populations Project

This study is currently recruiting participants.

Verified by Albert Einstein College of Medicine of Yeshiva University, June 2008

Sponsors and Collaborators:	Albert Einstein College of Medicine of Yeshiva University National Institutes of Health (NIH)
Information provided by:	Albert Einstein College of Medicine of Yeshiva University
ClinicalTrials.gov Identifier:	NCT00707694

Purpose

We believe extreme longevity is due to specific genes which function to delay aging and prevent disease. The purpose of our research is to identify the genes/mutations associated with healthier aging; to understand the biological functions of these genes/mutations; and to develop therapies to replicate these preservative genetic activities in individuals who do not have the genetic profile for longevity.

Condition
Extreme Longevity

U.S. FDA Resources

Study Type:	Observational
Study Design:	Case Control, Prospective
Official Title:	Searching for Longevity Genes in the Historically Unique Ashkenazi Jewish Population

Further study details as provided by Albert Einstein College of Medicine of Yeshiva University:

Biospecimen Retention: Samples With DNA

Biospecimen Description:

Estimated Enrollment:	1500
Study Start Date:	July 1998

Groups/Cohorts
Probands Ashkenazi Jews ages 95 and older
Offspring Ashkenazi Jewish offspring of Ashkenazi Jewish parent(s) who lived to at least the age of 95
Controls Ashkenazi Jewish people with no family history of longevity

Eligibility

Ages Eligible for Study:	65 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	Yes
Sampling Method:	Non-Probability Sample

Study Population

Ashkenazi Jews:

Ages 95 and older, their offspring and control group with no family history of longevity.

Criteria

Inclusion Criteria:

Ashkenazi Jewish, age 95+,
Offspring of person age 95+,
Offspring of parents who died age 70 or younger.

Exclusion Criteria:

Non-Ashkenazis

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00707694

Contacts

Contact: Deborah Davidson, MBA

718-430-3237

longevity@aecom.yu.edu

Locations

United States, New York
Hebrew Home Riverdale	Recruiting
Riverdale, New York, United States, 10471
Contact: Charlotte Dell, LMSW 718-581-1139

Sponsors and Collaborators

Albert Einstein College of Medicine of Yeshiva University

National Institutes of Health (NIH)

Investigators

Principal Investigator:

Nir Barzilai, MD

Albert Einstein College of Medicine of Yeshiva University

More Information

Responsible Party:	Albert Einstein College of Medicine of Yeshiva University ( Nir Barzilai, MD )
Study ID Numbers:	1998-125
Study First Received:	June 27, 2008
Last Updated:	June 30, 2008
ClinicalTrials.gov Identifier:	NCT00707694
Health Authority:	United States: Institutional Review Board

Keywords provided by Albert Einstein College of Medicine of Yeshiva University:

95 years of age and older

ClinicalTrials.gov processed this record on January 16, 2009