NINDS Neuroscience Funding Announcements

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Temporomandibular Joint and Muscle Disorders: Pathophysiological Mechanisms Linking Comorbid Conditions (R03)
Release Date: March 24, 2006
Announcement Number: PA-06-267
Application Receipt Date:
June 1, 2006
October 1, 2006
February 16, 2007
June 16, 2007
October 16, 2007
February 16, 2008
June 16, 2008
October 16, 2008
February 16, 2009   

Funding Contact: Linda Porter, Ph.D.
Program Area: Systems and Cognitive Neuroscience
Also See:  http://grants.nih.gov/grants/guide/notice-files/NOT-DE-06-003.html

Brief Description:
he purpose of this Funding Opportunity Announcement (FOA) is to stimulate research on discovering etiological and pathophysiological mechanisms underlying a set of chronic, comorbid conditions associated with temporomandibular joint and muscle disorders (TMJMDs). TMJMDs are a complex collection of diseases involving one or more tissues of the TMJ and facial musculature. Primary symptoms include chronic pain in facial muscles and limited and painful movement of the jaw. In addition, these and other symptoms of TMJMD can occur together with other chronic illnesses such as fibromyalgia, atypical face pain, trigeminal neuralgia, chronic fatigue syndrome, multiple chemical sensitivity, irritable bowel syndrome, complex regional pain syndrome, migraine headache, speech hearing, swallowing, balance, smell, and taste disorders, and certain cardiovascular diseases. This program announcement seeks research applications that use state-of-the-art, multidisciplinary and interdisciplinary approaches to discover molecular, physiological, and behavioral mechanisms responsible for the overlapping symptoms manifested in the set of disorders that may co-exist with TMJMD.

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