123I-MIBG SPECT/CT for Assessment of Cardiac Sympathetic Innervation

This study is not yet open for participant recruitment.

Verified by Rambam Health Care Campus, April 2007

Sponsored by:	Rambam Health Care Campus
Information provided by:	Rambam Health Care Campus
ClinicalTrials.gov Identifier:	NCT00296738

Purpose

Myocardial scintigraphy with 123I-MIBG allows for visual and semi-quantitative assessment of sympathetic cardiac innervation using the hear to mediastinum ratio (HMR). Impaired cardiac MIBG clearance may occur in patients with congestive heart failure (CHF). The purpose of present study was to develop and validate a quantitative index for the assessment of cardiac MIBG uptake kinetics using SPECT/CT for diagnosis of CHF

Condition	Intervention	Phase
Cardiac Diseases	Device: SPECT/CT	Phase 0

MedlinePlus related topics: Heart Diseases

U.S. FDA Resources

Study Type:	Observational
Study Design:	Screening, Longitudinal, Defined Population, Prospective Study
Official Title:	Quantitative 123I-MIBG SPECT/CT Assessment of Cardiac Sympathetic Innervation

Further study details as provided by Rambam Health Care Campus:

Estimated Enrollment:	19
Study Start Date:	May 2007
Estimated Study Completion Date:	May 2007

Eligibility

Ages Eligible for Study:	18 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

age>18

Exclusion Criteria:

none

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00296738

Contacts

Contact: Alex Frenkel, PhD

972-4-8542815

a_frenkel@rambam.health.gov.il

Locations

Israel
Rambam Medical Center
Haifa, Israel

Sponsors and Collaborators

Rambam Health Care Campus

Investigators

Principal Investigator:

Shmuel Rispler, MD PhD

Rambam Health Care Campus

More Information

Study ID Numbers:	MIBGCTIL
Study First Received:	February 24, 2006
Last Updated:	May 16, 2007
ClinicalTrials.gov Identifier:	NCT00296738
Health Authority:	Israel: Israeli Health Ministry Pharmaceutical Administration

Study placed in the following topic categories:

Heart Diseases

Additional relevant MeSH terms:

Cardiovascular Diseases

ClinicalTrials.gov processed this record on January 15, 2009