| Agent Name |
Dimethylamine |
|---|
| CAS Number |
124-40-3 |
|---|
| Formula |
C2-H7-N |
|---|
| Major Category |
Nitrogen Compounds |
|---|
| Synonyms |
Dimethylamine; Dimethylamine (anhydrous); Methanamine, N-methyl-; N,N-Dimethylamine; N-Methylmethanamine; [ChemIDplus] UN1032; UN1160 |
|---|
| Category |
Amines, Aliphatic |
|---|
| Description |
Colorless gas with an ammonia- or fish-like odor; Note: A liquid below 44 degrees F. Shipped as a liquefied compressed gas; [NIOSH] |
|---|
| Sources/Uses |
Used as an accelerator in the manufacturing of rubber, detergents, and pesticides; Used in leather tanning; [Merck Index # 3228] Used in electroplating, epoxy resin curing, textile manufacturing, photographic processing, hide dehairing, and pharmaceutical production; [HSDB] |
|---|
| Comments |
Liquid causes first degree burns on short exposure; [CHRIS] Corrosive to skin; [Quick CPC] Concentrations above 5420 ppm are lethal to mice with pulmonary hemorrhages and peripheral emphysema on pathological examination. [ACGIH] Pulmonary edema may result from inhalation of high concentrations. [NJ-HSFS] A lachrymator; [CHEMINFO] Animals suffer liver injury in high-dose experiments. [HSDB] |
|---|
| Exposure Assessment |
|---|
| Skin Designation (ACGIH) |
No |
|---|
| TLV (ACGIH) |
5 ppm |
|---|
| STEL (ACGIH) |
15 ppm |
|---|
| PEL (OSHA) |
10 ppm |
|---|
| MAK |
2 ppm |
|---|
| IDLH (NIOSH) |
500 ppm |
|---|
| Excerpts from Documentation for IDLHs |
Basis for revised IDLH: The revised IDLH for dimethylamine is 500 ppm based on acute inhalation toxicity data in animals [Steinhagen et al. 1982]. |
|---|
| Vapor Pressure |
1297 mm Hg |
|---|
| Odor Threshold Low |
0.00076 ppm |
|---|
| Odor Threshold High |
1.6 ppm |
|---|
| RD50 |
511 ppm |
|---|
| Lethal Concentration |
LC50 (rats) = 4,540 ppm/6H |
|---|
| Explanatory Notes |
Odor threshold from AIHA; The Guide from the Emergency Response Guidebook is for anhydrous dimethylamine. Flash point = 20 deg F; |
|---|
| Reference Link |
International Chemical Safety Cards (WHO/IPCS/ILO) |
|---|
| Flammability (NFPA) |
4: burns readily |
|---|
| Adverse Effects |
|---|
| Toxic Pneumonitis |
Yes |
|---|
| Dermatotoxin |
Skin Burns |
|---|
| Lacrimator |
Yes |
|---|
| Hepatotoxin |
Hepatotoxin, Secondary |
|---|
| Links to Other NLM Databases |
|---|
| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: DIMETHYLAMINE
|
|---|
