| Agent Name |
o-Phenylenediamine |
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| CAS Number |
95-54-5 |
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| Formula |
C6-H8-N2 |
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| Major Category |
Nitrogen Compounds |
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| Synonyms |
1,2-Benzenediamine; 1,2-Diaminobenzene; 1,2-Fenylendiamin [Czech] 1,2-Benzenediamine; 1,2-Diaminobenzene; 1,2-Fenylendiamin [Czech]; 1,2-Phenylenediamine; 2-Aminoaniline; C.I. 76010; C.I. Oxidation Base 16; CI 76010; CI Oxidation Base 16; OPDA; Orthamine; PODA; SQ 15500; o-Benzenediamine; o-Diaminobenzene; o-Fenylendiamin [Czech]; [ChemIDplus] UN1673 |
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| Category |
Amines, Aromatic |
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| Description |
Colorless to brownish-yellow solid that darkens on exposure to light and air; [CHEMINFO] |
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| Sources/Uses |
Used as a chemical intermediate, analytical reagent, and photographic developer; [CHEMINFO] |
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| Comments |
At lethal concentrations, exposed animals have seizures and paralysis without anesthesia. [ChemIDplus] Methemoglobinemia is observed in acute animal studies. In subchronic studies, rats have anemia and elevated liver enzymes. "Critical Effects" are irritation; liver; blood; [ACGIH] |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
No |
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| TLV (ACGIH) |
0.1 mg/m3 |
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| Lethal Concentration |
LC50 (rats) = 1,873 mg/m3 |
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| Explanatory Notes |
Melting point = 219 deg F; [CAMEO] |
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| Flammability (NFPA) |
1: must be preheated |
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| Adverse Effects |
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| Methemoglobinemia |
Methemoglobinemia, Secondary |
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| Hepatotoxin |
Hepatotoxin, Secondary |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: O-PHENYLENEDIAMINE
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