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Sponsored by: |
University of Pittsburgh |
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Information provided by: | University of Pittsburgh |
ClinicalTrials.gov Identifier: | NCT00258570 |
The purposes of this study are:
Condition |
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Pulmonary Fibrosis |
Study Type: | Observational |
Study Design: | Cohort |
Official Title: | Genetic Polymorphisms in Idiopathic Pulmonary Fibrosis |
Blood samples retained for multitude of testing. Consent allows for unrestricted use of samples.
Estimated Enrollment: | 1000 |
Study Start Date: | January 2003 |
Estimated Study Completion Date: | July 2010 |
Idiopathic pulmonary fibrosis is one of a collection of severe lung diseases that lead to abnormal inflammation and scarring of the lungs. The accumulation of scar tissue in the lung destroys normal lung tissue and results in the symptoms associated with this disease. The cause of the disease is currently unknown. In this study, we are attempting to determine if there are specific genetic traits that might explain why patients have developed pulmonary fibrosis. We are also attempting to determine if specific genetic traits account for differing patterns of inflammation and scar tissue that has formed in the patient's lungs. The purpose of this research is to identify genes that control the processes of lung inflammation, lung scarring, and lung repair. As more information becomes available, we will also conduct studies of additional genes that are found to be involved in this disease process.
Ages Eligible for Study: | 18 Years and older |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Sampling Method: | Non-Probability Sample |
Patient population includes patients who have been diagnosed with Idiopathic Pulmonary Fibrosis or other interstitial lung diseases who have been seen by a Simmons Center Physician
Inclusion Criteria:
Exclusion Criteria
Contact: Melinda J Seagriff, BA | 412-802-6860 ext 26860 | seagriffmj@upmc.edu |
Contact: Trisha R Black, BA | 412-605-1550 ext 51550 | blacktr@upmc.edu |
United States, Pennsylvania | |
University of Pittsburgh | Recruiting |
Pittsburgh, Pennsylvania, United States, 15213 | |
Sub-Investigator: Yingze Zhang, PhD | |
Sub-Investigator: Carol Feghali-Bostwick, PhD | |
Sub-Investigator: Sam Yousem, MD | |
Sub-Investigator: Rajiv Dhir, MD | |
Sub-Investigator: Prabir Ray, PhD | |
Sub-Investigator: Steven Duncan, MD | |
Sub-Investigator: Sean Studer, MD | |
Sub-Investigator: Ivan Rosas, M.D. | |
Sub-Investigator: Kathleen O. Lindell, R.N., M.S.N | |
Sub-Investigator: Melinda J Seagriff, B.A. | |
Sub-Investigator: Trisha R. Black, B.A. | |
Sub-Investigator: Ana H Taffel, B.S. | |
Sub-Investigator: Danielle Morse, M.D. | |
Sub-Investigator: Luis A Ortiz, M.D. |
Principal Investigator: | Kevin F Gibson, MD | University of Pittsburgh - Dorothy P. and Richard P. Simmons Center for Interstitial Lung Disease |
Principal Investigator: | Naftali Kaminski, M.D. | University of Pittsburgh - Dorothy P. and Richard P. Simmons Center for Interstitial Lung Disease |
Responsible Party: | University of Pittsburgh - Faculty ( Kevin Gibson, M.D. - Medical Director of the Simmons Center for ILD ) |
Study ID Numbers: | 020123 |
Study First Received: | November 23, 2005 |
Last Updated: | October 7, 2008 |
ClinicalTrials.gov Identifier: | NCT00258570 |
Health Authority: | United States: Institutional Review Board |
"Lung[A04.400]" |
Lung Diseases, Interstitial Respiratory Tract Diseases Fibrosis |
Hamman-Rich syndrome Lung Diseases Pulmonary Fibrosis |
Pathologic Processes |