Diagnosis and Characterization of Coronary Artery Stenosis by Doppler Ultrasound

This study is not yet open for participant recruitment.

Verified by Hillel Yaffe Medical Center, March 2007

Sponsored by:	Hillel Yaffe Medical Center
Information provided by:	Hillel Yaffe Medical Center
ClinicalTrials.gov Identifier:	NCT00521326

Purpose

The purpose of this study is to evaluate the feasibility of acquisition of coronary blood flow velocity signals over the whole length of the LAD with transthoracic pulsed Doppler, and to evaluate the diagnostic power of the transthoracic Doppler analysis package for detecting and estimating the degree of coronary artery stenosis. Finally we hope to optimize the currently available analysis package on the basis of the comparison of the Doppler with the angiographic stenosis results and evaluation.

Condition
Coronary Stenosis

MedlinePlus related topics: Ultrasound

U.S. FDA Resources

Study Type:	Observational
Study Design:	Screening, Cross-Sectional, Defined Population, Prospective Study
Official Title:	Diagnosis and Characterization of Coronary Artery Stenosis by Transthoracic Doppler Ultrasound

Further study details as provided by Hillel Yaffe Medical Center:

Study Start Date:

August 2007

Groups/Cohorts
A: Case Patients with an acute coronary syndrome that are candidates for coronary angiography. Doppler results will be compared to angiographic findings.

Eligibility

Ages Eligible for Study:	18 Years and older
Genders Eligible for Study:	Both

Criteria

Inclusion Criteria:

Patients who are clinically suspected of having significant coronary artery stenosis.
Patients with CAD.
Patients who are scheduled to undergo coronary angiography.
Signed informed consent.

Exclusion Criteria:

Patients with arrhythmia / irregular pulse
Patients with unstable conditions: unstable angina, uncontrolled CHF
Patients with COPD
Any physical or medical disability that prevent lying in supine position
Patients with chest wall deformity

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00521326

Contacts

Contact: Simcha R Meisel, MD, MSc	972-4-630-4656	meisel@hy.health.gov.il
Contact: Avraham Shotan, MD	972-4-630-4428	shotana@yahoo.com

Locations

Israel
Coronary Care Unit, Heart Institute, Hille Yaffe Medical Center
Hadera, Israel, 38100

Sponsors and Collaborators

Hillel Yaffe Medical Center

Investigators

Principal Investigator:

Simcha R Meisel, MD, MSc

Hillel Yaffe Medical Center

More Information

Study ID Numbers:	DOP01
Study First Received:	August 24, 2007
Last Updated:	August 24, 2007
ClinicalTrials.gov Identifier:	NCT00521326
Health Authority:	Israel: Ministry of Health

Keywords provided by Hillel Yaffe Medical Center:

doppler
coronary stenosis
non-invasive testing
A prospective study of a new diagnostic method.

Study consists of a transthoracic doppler of LAD.
Doppler to be performed prior to coronary angiography.
F/U doppler examination for those who undergo PCI.
Doppler results will be compared with coronary angiography.

Study placed in the following topic categories:

Coronary Disease
Pathological Conditions, Anatomical
Heart Diseases
Myocardial Ischemia
Vascular Diseases

Constriction, Pathologic
Ischemia
Coronary Stenosis
Coronary Artery Disease

Additional relevant MeSH terms:

Cardiovascular Diseases

ClinicalTrials.gov processed this record on January 16, 2009