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Procedural Learning in Participants With ADHD
This study is not yet open for participant recruitment.
Verified by Shaare Zedek Medical Center, January 2007
Sponsored by: Shaare Zedek Medical Center
Information provided by: Shaare Zedek Medical Center
ClinicalTrials.gov Identifier: NCT00446537
  Purpose

Skill acquisition refers to the process of improvement of performance following practice experience. This process is the basis for generation of a long-lasting memory. Individuals with Attention Deficit Hyperactivity Disorder (ADHD) have been shown to be impaired on some performance aspects of previously learned skills, an impairment that is often ameliorated, at least temporarily, by psychostimulant medication (the standard therapy in ADHD). The proposed study aims to define the course of learning and of generation of long-term memory consolidation in individuals with ADHD, and to essay the effectiveness of psychostimulant medication on both the learning and retention of the skills.


Condition Intervention Phase
Attention Deficit Hyperactivity Disorder
Procedure: Methylphenidate
Phase 0

MedlinePlus related topics: Attention Deficit Hyperactivity Disorder Memory
Drug Information available for: Methylphenidate hydrochloride Methylphenidate
U.S. FDA Resources
Study Type: Interventional
Study Design: Randomized, Double-Blind, Placebo Control, Crossover Assignment

Further study details as provided by Shaare Zedek Medical Center:

Detailed Description:

Skill Acquisition and the Evolution of Long Term Procedural Memory in participants with ADHD: The Effect of Methylphenidate

  Eligibility

Ages Eligible for Study:   12 Years to 50 Years
Genders Eligible for Study:   Both
Criteria

Inclusion Criteria:

  • Full scale IQ score of 85 or above
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00446537

Contacts
Contact: Esther Adi-Japha, PhD 972-3-5318704 japhae@mail.biu.ac.il

Locations
Israel
Neuropediatric Unit
Jerusalem, Israel, 91031
Sponsors and Collaborators
Shaare Zedek Medical Center
Investigators
Principal Investigator: Esther Adi-Japha, PhD Bar-Ilan University, Israel
Study Chair: Ruth Shalev, MD Shaare Zedek Medial Center
  More Information

Study ID Numbers: 240446
Study First Received: March 11, 2007
Last Updated: March 12, 2007
ClinicalTrials.gov Identifier: NCT00446537  
Health Authority: Israel: Ethics Commission

Keywords provided by Shaare Zedek Medical Center:
Skill Acquisition and the Evolution of Long Term Procedural Memory in participants with ADHD: The Effect of Methylphenidate

Study placed in the following topic categories:
Signs and Symptoms
Dopamine
Attention Deficit Disorder with Hyperactivity
Mental Disorders
Mental Disorders Diagnosed in Childhood
Methylphenidate
Attention Deficit and Disruptive Behavior Disorders
Neurologic Manifestations
Hyperkinesis
Dyskinesias

Additional relevant MeSH terms:
Dopamine Uptake Inhibitors
Neurotransmitter Uptake Inhibitors
Neurotransmitter Agents
Molecular Mechanisms of Pharmacological Action
Therapeutic Uses
Physiological Effects of Drugs
Nervous System Diseases
Central Nervous System Stimulants
Dopamine Agents
Central Nervous System Agents
Pharmacologic Actions

ClinicalTrials.gov processed this record on January 16, 2009