The MBC Associations Searcher finds:

• Molecular biology associations that relate chromosomal aberrations and tumor histologies to genomic sequence data, typically genes rearranged as a consequence of structural chromosome changes.
• Clinical associations that relate chromosomal aberrations and/or gene rearrangements and tumor histologies to clinical variables, such as prognosis, tumor grade, and patient characteristics.

MBC Associations Searcher

Brief instructions for using the MBC Associations Searcher:

• Select an Association.
• Complete as many of the fields following as required.
• The default setting for both Topography and Morphology is all items. Or highlight single or multiple items.
• Any section may be left blank.
• Press Submit Query, or Reset to begin a new search.

Association

Molecular Biology   Clinical

Cytogenetic Characteristics

Abnormality:	And Or
Breakpoint:	And Or

Gene Characteristics

Gene:

And Or

Tumor Characteristics

Topography:	Adrenal Anus Bladder Blood vessel Bone and soft tissues (all sites) Brain stem Brain Breast (all sites) Breast Cardiovascular system (all sites) Central nervous system (all sites) Cerebellum Digestive system (all sites) Endocrine system (all sites) Eye Fallopian tube Female genital organs (all sites) Gallbladder/Biliary system Heart Hypothalamus Intraabdominal Intrathoracal Kidney Large intestine Larynx Lip Liver Lung Lymph node Lymphatic system (all sites) Male genital organs (all sites) Nasal cavity/Paranasal sinuses Nasopharynx Oesophagus Oral cavity Oro- and hypopharynx Ovary Pancreas Parathyroid Penis Peritoneum Pineal body Pituitary Pleura Prostate Respiratory system (all sites) Salivary gland Skeleton Skin (all sites) Skin Small intestine Soft tissue Spinal cord Spleen Stomach Teeth Testis Thymus Thyroid Tongue Unknown site Ureter Urethra Urinary tract (all sites) Uterus, cervix Uterus, corpus Vagina
Morphology:	Acinic cell carcinoma Acute basophilic leukemia Acute eosinophilic leukemia Acute erythroleukemia (FAB type M6) Acute lymphoblastic leukemia/lymphoblastic lymphoma Acute megakaryoblastic leukemia (FAB type M7) Acute monoblastic leukemia (FAB type M5) Acute monoblastic leukemia with differentiation (FAB type M5b) Acute monoblastic leukemia without differentiation (FAB type M5a) Acute myeloblastic leukemia with maturation (FAB type M2) Acute myeloblastic leukemia with minimal differentiation (FAB type M0) Acute myeloblastic leukemia without maturation (FAB type M1) Acute myeloid leukemia (all subtypes) Acute myeloid leukemia, NOS Acute myeloid leukemia, special type Acute myelomonocytic leukemia (FAB type M4) Acute panmyelosis with myelofibrosis Acute promyelocytic leukemia (FAB type M3) Acute undifferentiated leukemia Adamantinoma Adenocarcinoma Adenoid cystic carcinoma Adenoma Adenosquamous carcinoma Adipocytic tumor, NOS Adipocytic tumors (all subtypes) Adipocytic tumor, special type Adult T-cell lymphoma/leukemia (HTLV-1+) Aggressive NK-cell leukemia Alveolar rhabdomyosarcoma Alveolar soft part sarcoma Anaplastic large cell lymphoma, cutaneous type Anaplastic large cell lymphoma, systemic type Aneurysmal bone cyst Angiofibroma Angioimmunoblastic T-cell lymphoma Angiolipoma Angiomatoid malignant fibrous histiocytoma Angiomyolipoma Angiosarcoma Astrocytoma, grade III-IV Astrocytoma, grade I-II Astrocytoma, NOS Astrocytoma, pilocytic/juvenile Atypical chronic myeloid leukemia Atypical lipomatous tumor/atypical lipoma/well-differentiated liposarcoma Basal cell carcinoma B-cell lymphoma associated with hemophagocytic syndrome Benign epithelial neoplasms (all subtypes) Benign epithelial tumor, NOS Benign epithelial tumor, special type Benign fibrous histiocytoma Benign nevus Bilineage or biphenotypic leukemia B-prolymphocytic leukemia Burkitt lymphoma/leukemia Carcinoid tumor Carcinoma in situ Carcinoma, NOS Cartilage tumor, NOS Cartilage tumors (all subtypes) Cartilage tumor, special type Chondroblastoma Chondroid hamartoma Chondroid lipoma Chondroma Chondromyxoid fibroma Chondrosarcoma, clear cell Chondrosarcoma, dedifferentiated Chondrosarcoma, mesenchymal Chondrosarcoma, myxoid Chondrosarcoma, NOS Chordoma Choroid plexus papilloma/carcinoma Chronic eosinophilic leukemia/hypereosinophilic syndrome Chronic lymphocytic leukemia Chronic myeloid leukemia, aberrant translocation Chronic myeloid leukemia (all subtypes) Chronic myeloid leukemia, t(9;22) Chronic myelomonocytic leukemia Chronic myeloproliferative disorder, NOS Chronic myeloproliferative disorders (all subtypes) Chronic myeloproliferative disorder, special type Chronic neutrophilic leukemia Clear cell sarcoma Combined germ cell tumors Dendritic cell neoplasm Dermatofibrosarcoma protuberans/Bednar tumor/giant cell fibroblastoma Desmoid-type fibromatosis Desmoplastic small round cell tumor Diffuse large B-cell lymphoma Diffuse-type giant cell tumor Dysplasia Dysplastic nevus Embryonal nervous system tumor, NOS Embryonal nervous system tumors (all subtypes) Embryonal nervous system tumor, special type Embryonal rhabdomyosarcoma Endometrial stromal sarcoma Enteropathy-type T-cell lymphoma Ependymoma Epithelioid sarcoma Essential thrombocythemia Ewing tumor/peripheral primitive neuroectodermal tumor Extranodal marginal zone B-cell lymphoma Extranodal NK/T-cell lymphoma Fasciitis Fibroblastic/myofibroblastic tumor, NOS Fibroblastic/myofibroblastic tumors (all subtypes) Fibroblastic/myofibroblastic tumor, special type Fibrohistiocytic tumor, NOS Fibrohistiocytic tumors (all subtypes) Fibrohistiocytic tumor, special type Fibroma Fibromyxoid sarcoma Fibrosarcoma/sclerosing epithelioid fibrosarcoma Fibrous dysplasia Follicular lymphoma Gastrointestinal stromal tumor Germ cell and gonadal stromal cell neoplasms (all subtypes) Germ cell tumor, NOS Germ cell tumor, special type Giant cell tumor of bone Glioma, NOS Glomus tumor Gonadal stromal cell tumors Hairy cell leukemia Heavy chain disease Hemangioendothelioma Hemangioma/lymphangioma Hemangiopericytoma Hepatoblastoma Hepatosplenic T-cell lymphoma Hibernoma Histiocytic sarcoma/malignant histiocytosis Hodgkin disease (all subtypes) Hodgkin disease, lymphocyte depletion Hodgkin disease, lymphocyte predominance Hodgkin disease, mixed cellularity Hodgkin disease, nodular sclerosis Hodgkin disease, NOS Hyperplasia Idiopathic myelofibrosis Inflammatory myofibroblastic tumor/myofibroblastic sarcoma Intimal sarcoma Intravascular large B-cell lymphoma Juvenile myelomonocytic leukemia Kaposi sarcoma Langerhans cell histiocytosis Leiomyoma Leiomyosarcoma Lipoblastoma Lipoma Liposarcoma, dedifferentiated Liposarcoma, myxoid/round cell Liposarcoma, NOS Liposarcoma, pleomorphic Localized giant cell tumor of tendon sheath Lymphoblastic leukemia/lymphoma, special type Lymphoplasmacytic lymphoma Malignant epithelial neoplasms (all subtypes) Malignant epithelial tumor, special type Malignant fibrous histiocytoma Malignant melanoma Malignant peripheral nerve sheath tumor/Triton Mantle cell lymphoma Mastocytosis Mature B-cell neoplasm, NOS Mature B-cell neoplasms (all subtypes) Mature B-cell neoplasm, special type Mature T- and NK-cell neoplasm, NOS Mature T- and NK-cell neoplasms (all subtypes) Mature T- and NK-cell neoplasm, special type Mediastinal large B-cell lymphoma Melanocytic neoplasms (all subtypes) Melanocytic neoplasm, special type Meningioma Merkel cell carcinoma Mesenchymal tumor, NOS Mesenchymal tumor, special type Mesenchymoma Mesoblastic nephroma Mesothelioma Metaplasia Metaplastic carcinoma Miscellaneous hematopoietic/lymphoid neoplasms (all subtypes) Miscellaneous mesenchymal tumors (all subtypes) Miscellaneous soft tissue tumors (all subtypes) Monoclonal gammopathy of undetermined significance Mucoepidermoid carcinoma Multiple myeloma Muscle tumor, NOS Muscle tumors (all subtypes) Muscle tumor, special type Mycosis fungoides/Sézary syndrome Myelodysplastic/myeloproliferative disease (all subtypes) Myelodysplastic/myeloproliferative disease, NOS Myelodysplastic/myeloproliferative disease, special type Myelodysplastic syndrome, NOS Myelodysplastic syndromes (all subtypes) Myelodysplastic syndrome, special type Myogenic sarcoma, NOS Myolipoma Myositis Myxofibrosarcoma Myxoma Neuroblastoma Neurofibroma Neuroglial neoplasms (all subtypes) Neuroglial neoplasm, special type Nevus, NOS Nodal marginal zone B-cell lymphoma Nonneoplastic disorder/lesion, special type Nonneoplastic disorders/lesions (all subtypes) Nonneoplastic epithelial disorder/lesion Nonneoplastic lymphatic disorder/lesion Nonneoplastic mesenchymal disorder/lesion Nonneoplastic myeloid disorder/lesion Nonneoplastic neurogenic disorder/lesion Oligodendroglioma Oncocytoma Osteoblastoma Osteochondroma Osteofibrous dysplasia Osteogenic/bone tumor, NOS Osteogenic/bone tumor, special type Osteogenic/miscellaneous bone tumors (all subtypes) Osteoid osteoma Osteosarcoma, NOS Osteosarcoma, parosteal Osteosarcoma, periosteal Osteosarcoma, small cell Osteosarcoma, telangiectatic Papilloma Parachordoma Perineurioma Peripheral neuroepithelioma Peripheral T-cell lymphoma, unspecified Phyllodes tumor, benign Phyllodes tumor, malignant Plasma cell leukemia Plasma cell neoplasm, NOS Plasma cell neoplasms (all subtypes) Plasma cell neoplasm, special type Plasmacytoma Pleomorphic rhabdomyosarcoma Polycythemia vera Post-transplant lymphoproliferative disorder Precursor lymphoblastic leukemia/lymphoma (all subtypes) Primary amyloidosis Primary effusion lymphoma Primitive neuroectodermal tumor/Medulloblastoma Refractory anemia Refractory anemia with excess blasts-1 Refractory anemia with excess blasts-2 Refractory anemia with excess of blasts (FAB) Refractory anemia with ringed sideroblasts Refractory cytopenia with multilineage dysplasia and ringed sideroblasts Refractory cytopenia with multilineage dysplasia Retinoblastoma Rhabdoid tumor Rhabdomyoma Rhabdomyosarcoma, NOS Schwannoma Seminoma/Dysgerminoma Soft tissue tumor, NOS Soft tissue tumor, special type Solitary fibrous tumor Spindle cell/pleomorphic lipoma Splenic marginal zone B-cell lymphoma Squamous cell carcinoma Subcutaneous panniculitis-like T-cell lymphoma Superficial fibromatosis Synovial chondromatosis Synovial sarcoma T-cell granular lymphocytic leukemia Teratoma (mature and immature) T-prolymphocytic leukemia Transitional cell carcinoma Undifferentiated and biphenotypic leukemia (all subtypes) Undifferentiated carcinoma, large cell Undifferentiated carcinoma Undifferentiated carcinoma, small cell Vascular and perivascular tumor, NOS Vascular and perivascular tumors (all subtypes) Vascular and perivascular tumor, special type Waldenström macroglobulinemia Warthin tumor Wilms tumor
Immunophenotype:	B Lineage T Lineage

Reference

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Specific ID Number:	Ref. No. Inv. No.
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