Proton MR Spectroscopy of Brain Metastases in Evaluation of Treatment Response.

This study is enrolling participants by invitation only.

Sponsors and Collaborators:	Norwegian University of Science and Technology The Royal Norwegian Ministry of Health
Information provided by:	Norwegian University of Science and Technology
ClinicalTrials.gov Identifier:	NCT00184288

Purpose

The aim of the study is to investigate the feasibility of in vivo single volume MR spectroscopy in evaluation of treatment response in patients with brain metastases, using 3T MR instrument. In order to optimize and avoid ineffective treatment of patients with brain metastases, in vivo MR spectroscopy can be an useful tool.

Condition
Neoplasm Metastasis Lung Neoplasms Breast Neoplasms Melanoma

Genetics Home Reference related topics: breast cancer

MedlinePlus related topics: Breast Cancer Cancer Lung Cancer Melanoma

Drug Information available for: Lipids Choline Choline bitartrate Choline chloride Choline dihydrogen citrate Choline salicylate

U.S. FDA Resources

Study Type:	Observational
Study Design:	Case-Only, Prospective
Official Title:	Single Volume 1H MR Spectroscopy of Brain Metastases in Evaluation of Treatment Response.

Further study details as provided by Norwegian University of Science and Technology:

Biospecimen Retention: None Retained

Biospecimen Description:

Estimated Enrollment:	50
Study Start Date:	November 2004
Estimated Study Completion Date:	December 2010
Primary Completion Date:	June 2006 (Final data collection date for primary outcome measure)

Eligibility

Ages Eligible for Study:	18 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No
Sampling Method:	Non-Probability Sample

Study Population

patients with brain metastases

Criteria

Inclusion Criteria:

Clinical diagnosis of brain metastases

Exclusion Criteria:

children
pregnancy

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00184288

Locations

Norway
Norwegian University of Science and Technology, Faculty of Medicine
Trondheim, Norway, N-7489

Sponsors and Collaborators

Norwegian University of Science and Technology

The Royal Norwegian Ministry of Health

Investigators

Study Director:

Steinar Lundgren, MD PhD

Cancer clinic, St.Olavs Hospital Trondheim University Hospital

More Information

Responsible Party:	Faculty of Medicine ( Norwegian University of Science and Technology )
Study ID Numbers:	11184
Study First Received:	September 13, 2005
Last Updated:	January 23, 2008
ClinicalTrials.gov Identifier:	NCT00184288
Health Authority:	Norway: Norwegian Social Science Data Services

Keywords provided by Norwegian University of Science and Technology:

Lipid
choline
metastasis
magnetic resonance spectroscopy
treatment response

Study placed in the following topic categories:

Thoracic Neoplasms
Choline
Skin Diseases
Breast Neoplasms
Melanoma
Neuroendocrine Tumors
Neuroectodermal Tumors
Respiratory Tract Diseases

Lung Neoplasms
Nevus, Pigmented
Lung Diseases
Neoplasms, Germ Cell and Embryonal
Neoplasm Metastasis
Neuroepithelioma
Nevus
Breast Diseases

Additional relevant MeSH terms:

Respiratory Tract Neoplasms
Neoplastic Processes
Neoplasms
Pathologic Processes

Neoplasms by Histologic Type
Neoplasms by Site
Neoplasms, Nerve Tissue
Nevi and Melanomas

ClinicalTrials.gov processed this record on January 14, 2009