ARTIST: ARThrose Intervention STandardisée - Full Text View

Sponsored by:	Almirall, SAS
Information provided by:	Almirall, SAS
ClinicalTrials.gov Identifier:	NCT00462319

Purpose

International recommendations (ACR,EULAR) emphasize physical exercise and weight loss for patients suffering from knee osteoarthritis. Nevertheless, number of patients receiving advices for these 2 points still low. This study evaluates the impact of a standardized medical intervention (patient education, weight reduction and physical exercise) in knee osteoarthritis patients.

Condition	Intervention	Phase
Knee Osteoarthritis	Behavioral: Education, weight reduction and physical exercise	Phase IV

MedlinePlus related topics: Exercise and Physical Fitness Joint Disorders Osteoarthritis Weight Control

U.S. FDA Resources

Study Type:	Interventional
Study Design:	Educational/Counseling/Training, Randomized, Open Label, Active Control, Parallel Assignment, Efficacy Study
Official Title:	Evaluation of Standardized Management of Knee Arthritis Patients

Further study details as provided by Almirall, SAS:

Primary Outcome Measures:

Weight
Physical Exercise in Leisure

Study Start Date:

May 2005

Eligibility

Ages Eligible for Study:	45 Years to 75 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

symptomatic and ambulatory patients
suffering from knee osteoarthritis (ACR criteria)
25<BMI<35
signed informed consent

Exclusion Criteria:

need to surgery within 6 next months
co-morbidity

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00462319

Locations

France

Paris, France

Sponsors and Collaborators

Almirall, SAS

Investigators

Principal Investigator:

René Marc FLIPO

Hôpital Salengro - Lille, France

More Information

Publications:

[No authors listed] Recommendations for the medical management of osteoarthritis of the hip and knee: 2000 update. American College of Rheumatology Subcommittee on Osteoarthritis Guidelines. Arthritis Rheum. 2000 Sep;43(9):1905-15. No abstract available.

Messier SP, Gutekunst DJ, Davis C, DeVita P. Weight loss reduces knee-joint loads in overweight and obese older adults with knee osteoarthritis. Arthritis Rheum. 2005 Jul;52(7):2026-32.

Study ID Numbers:	2004/07
Study First Received:	April 18, 2007
Last Updated:	April 18, 2007
ClinicalTrials.gov Identifier:	NCT00462319
Health Authority:	France: Person Protection Committee CPP

Study placed in the following topic categories:

Osteoarthritis, Knee
Musculoskeletal Diseases
Osteoarthritis

Arthritis
Joint Diseases
Rheumatic Diseases

ClinicalTrials.gov processed this record on January 16, 2009