|
National Institutes of Health |
 |
 |
 |
 |
 |
 |
 |
|
|
|
Quick Links
|
High-End Instrumentation Grants - July 16, 2008ON THIS PAGE:
SEE ALSO: NCRR's High-End Instrumentation (HEI) grant program supports the purchase of research equipment that costs more than $750,000. Instruments in this price range include structural and functional imaging systems, macromolecular NMR spectrometers, high-resolution mass spectrometers, electron microscopes, and supercomputers. The Brigham and Women's Hospital, Inc.Boston, MA
Award: $2,000,000 A secondary ion mass spectrometer for quantitative intracellular stable isotope imaging provides a revolutionary new approach to cellular visualization and will help solve difficult problems in practically all fields of biomedical research. Florida State UniversityTallahassee, FL Award: $2,000,000 A 3-D cryo-electron microscope for fully automated 3-D imaging of complex biological structures at the molecular level will be a critical tool to support research in heart disease, hypertension, cancer, gene therapy vectors, lipoprotein diseases, and HIV/AIDS. Immune Disease InstituteFormerly known as the CBR Institute for Biomedical Research Award: $952,390 A continuous wave and pulsed electron paramagnetic resonance spectrometer is a powerful tool to study and characterize the structure and function of important membrane protein complexes involved in the etiology and treatment of Alzheimer's disease, rheumatoid arthritis, asthma, various cancers, and HIV/AIDS. Indiana University BloomingtonBloomington, IN Award: $927,375 A high throughput confocal imaging system for rapid screening of large numbers of fluorescently labeled live cell samples will aid in the potential development of new cancer and antibiotic therapies. Johns Hopkins UniversityBaltimore, MD Award: $2,000,000 A large memory cluster computer at the Institute for Computational Medicine will dramatically accelerate the creation and use of computational models and algorithms for the early diagnosis and treatment of a variety of diseases, including brain disease, heart disease, and cancer. Northwestern UniversityEvanston, IL Award: $1,900,000 A high-powered (300 kV) field emission cryo-electron microscope, a powerful new tool with increased imaging abilities, will help reveal molecular and cellular targets for new therapies for multiple brain disorders, cancers, and infectious diseases. Managed by the Biological Imaging Facility on the Evanston campus, this new microscope will be an important resource available to researchers throughout Northwestern University. Northwestern UniversityEvanston and Chicago, IL Award: $2,000,000 To be situated at the Feinberg School of Medicine on Northwestern's Chicago campus, a 7-Tesla magnetic resonance scanner for small animal imaging will provide high-quality pictures to understand the progression and clarify the mechanisms underlying a variety of diseases, such as Alzheimer's disease, cancer, and heart disease. The State University of New York Stony BrookStony Brook, NY Award: $850,874 A orbital trap mass spectrometer with extremely high resolving power will enable researchers to discover and characterize proteins and novel diagnostic biomarkers in diabetes, cancer, heart disease, and other major diseases. Translational Genomics Research InstitutePhoenix, AZ Award: $1,996,810 This highly-parallel supercomputing equipment for translational research improves researchers' speed and efficiency for identifying biomarkers useful in diagnosing diseases such as autism, Alzheimer's, melanoma, cancer, and heart disease. University of Illinois at Urbana — ChampaignChampaign, IL Award: $1,936,449 A state-of-the-art high-field, wide-bore, solid-state nuclear magnetic resonance spectrometer will support collaborative research on the structures of membrane proteins involved in diseases such as Parkinson's, diabetes, and HIV/AIDS. University of MinnesotaMinneapolis, MN Award: $2,000,000 An ultra-high-field (16.4-Tesla) animal magnetic resonance imaging and spectroscopy system—the first of its kind in the United States—will offer the highest magnetic field available for animal studies. Through improved sensitivity and resolution, the system will serve as a valuable tool, enabling researchers to better understand a variety of brain diseases. University of MinnesotaMinneapolis, MN Award: $1,229,450 An automated, high-throughput nanoliter crystallization platform for making high-quality crystals from nanoliters of purified protein complexes will be extremely valuable in studying Alzheimer's disease, cancer, and other clinical research investigations where specimen size is limiting. The University of North Carolina at Chapel HillChapel Hill, NC Award: $2,000,000 A 3-Tesla whole-body magnetic resonance (MR) scanner with parallel processing will shorten the time needed to collect high-quality MR images—especially important in pediatric studies. The scanner will also be compatible with the university's existing hospital scanners. With imaging as a key component of the university's Translational and Clinical Science Institute funded by an NCRR Clinical and Translational Science Award, the new scanner will greatly improve the ability to directly translate research imaging projects into the clinical arena. University of PennsylvaniaPhiladelphia, PA Award: $2,000,000 A cyclotron for producing novel radioisotopes will provide clinical researchers at the University of Pennsylvania, especially at the Institute for Translational Medicine and Therapeutics (ITMAT), with unique diagnostic tools for cancer studies. Funded by the NCRR Clinical and Translational Science Award (CTSA) program, the ITMAT Imaging Probe Synthesis Core is a critical part of ITMAT's Translational Biomedical Imaging Center, providing imaging probes to the CTSA research community. University of PittsburghPittsburgh, PA Award: $2,000,000 A positron emission tomography (PET) insert for an existing 3-Tesla magnetic resonance (MR) scanner that allows simultaneous collection of PET and MR brain images will offer scientists new ways to investigate the progression of certain types of brain cancers and a variety of neurological studies, thereby providing insight into Alzheimer's and Parkinson's disease processes. University of VirginiaCharlottesville, VA Award: $1,992,300 A cyclotron for producing radiotracers will enable research that is now not currently possible on new ways of detecting, characterizing, and treating diseases such as heart disease, cancer, and diabetes, using positron emission tomography (PET) and single gamma emission tomography (SPECT) scanning. The University of Wisconsin — MadisonMadison, WI Award: $1,665,930 This integrated state-of-the-art liquid-chromatography system, mass spectrometer, and nuclear magnetic resonance spectrometer combines three different useful technologies into a single analytical platform offering potential impact in metabolic profiling, biomarker discovery, and studies of natural products and molecular interactions. Vanderbilt UniversityNashville, TN Award: $988,312 This award will allow for the purchase of a robotic storage and distribution system for a very large-scale biobank designed to enable exploration of genotype-phenotype relations in humans with a wide range of diseases. The Vanderbilt DNA Databank is a critical component to the Vanderbilt Institute for Clinical and Translational Research (VICTR), and this new system will dramatically accelerate the rate at which the resource can be accessed by translational researchers. This important new system provides a vital first step in moving the emerging sciences of genomics and pharmacogenomics from research tools to clinical practice, a key function of the VICTR, which is also funded by NCRR through its Clinical and Translational Science Award program. Washington State UniversityPullman, WA Award: $989,825 A high-throughput Fourier Transform ion cyclotron resonance mass spectrometer and automated liquid chromatography system will help researchers better understand protein synthesis, function, and interactions at the cellular level. This system will help support research in cancer biology, reproductive biology, and immunology. Washington University in St. LouisSt. Louis, MO Award: $1,879,719 A high-field (12-Tesla) Fourier Transform mass spectrometer will provide unparalleled capabilities to understand a broad array of biomedical conditions that impact human health including arthritis, autoimmunity, diabetes, HIV, blood disorders, anesthesiology, and general biological processes. The mass spectrometer will be housed in the Resource for Biomedical and Bio-Organic Mass Spectrometry at the university and will be used, in part, to support collaborative research in the Washington University Institute of Clinical and Translational Sciences, funded through an NCRR Clinical and Translational Science Award. Contact InformationDr. Marjorie A. Tingle |
 |
National Institutes of Health (NIH) Bethesda, Maryland 20892 |
 |
Department of Health and Human Services |
 |
