The Treatment and Natural History of Acromegaly - Full Text View

Sponsored by:	National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Information provided by:	National Institutes of Health Clinical Center (CC)
ClinicalTrials.gov Identifier:	NCT00001981

Purpose

The purpose of this study is to investigate the treatment and natural history of acromegaly. We have a longstanding interest in acromegaly treatment, and a cohort that has been followed for 30 years, or more in some cases. We will continue to follow patients and recruit new patients for treatment and follow-up. Blood and pituitary tumor tissue (when available through clinical care) will be saved for future analyses related to acromegaly.

Condition
Acromegaly Pituitary Neoplasm

MedlinePlus related topics: Cancer

Drug Information available for: Ursodeoxycholic acid Somatostatin

U.S. FDA Resources

Study Type:	Observational
Official Title:	Acromegaly Treatment and Natural History

Further study details as provided by National Institutes of Health Clinical Center (CC):

Study Start Date:

April 1985

Detailed Description:

The purpose of this study is to investigate the treatment and natural history of acromegaly. We have a longstanding interest in acromegaly treatment, and a cohort that has been followed for 30 years, or more in some cases. We will continue to follow patients and recruit new patients for treatment and follow-up. Blood and pituitary tumor tissue (when available through clinical care) will be saved for future analyses related to acromegaly.

Eligibility

Ages Eligible for Study:	18 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

INCLUSION CRITERIA:

Patients will be enrolled who are 18 years of age or over who are referred for care.

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00001981

Contacts

Contact: Patient Recruitment and Public Liaison Office	(800) 411-1222	prpl@mail.cc.nih.gov
Contact: TTY	1-866-411-1010

Locations

United States, Maryland
National Institutes of Health Clinical Center, 9000 Rockville Pike	Recruiting
Bethesda, Maryland, United States, 20892

Sponsors and Collaborators

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

More Information

NIH Clinical Center Detailed Web Page This link exits the ClinicalTrials.gov site

Publications:

Eastman RC, Gorden P, Glatstein E, Roth J. Radiation therapy of acromegaly. Endocrinol Metab Clin North Am. 1992 Sep;21(3):693-712. Review.

Gorden P, Comi RJ, Maton PN, Go VL. NIH conference. Somatostatin and somatostatin analogue (SMS 201-995) in treatment of hormone-secreting tumors of the pituitary and gastrointestinal tract and non-neoplastic diseases of the gut. Ann Intern Med. 1989 Jan 1;110(1):35-50. Review.

Eastman RC, Arakaki RF, Shawker T, Schock R, Roach P, Comi RJ, Gorden P. A prospective examination of octreotide-induced gall-bladder changes in acromegaly. Clin Endocrinol (Oxf). 1992 Mar;36(3):265-9.

Study ID Numbers:	850082, 85-DK-0082
Study First Received:	January 21, 2000
Last Updated:	December 12, 2008
ClinicalTrials.gov Identifier:	NCT00001981
Health Authority:	United States: Federal Government

Keywords provided by National Institutes of Health Clinical Center (CC):

Somatostatin Analogue
Acromegaly
TSH Producing Tumor
Islet Cell Tumor

Ursodeoxycholate
Pituitary
Irradiation
Treatment

Study placed in the following topic categories:

Bone Diseases, Endocrine
Hypothalamic Diseases
Pituitary Diseases
Central Nervous System Diseases
Endocrine System Diseases
Central Nervous System Neoplasms
Pituitary Neoplasms
Brain Diseases
Bone Diseases
Supratentorial Neoplasms

Somatostatin
Ursodeoxycholic Acid
Brain Neoplasms
Musculoskeletal Diseases
Endocrinopathy
Pancreatic islet cell tumors
Nervous System Neoplasms
Acromegaly
Endocrine Gland Neoplasms

Additional relevant MeSH terms:

Neoplasms
Neoplasms by Site
Hyperpituitarism
Hypothalamic Neoplasms
Nervous System Diseases

ClinicalTrials.gov processed this record on January 15, 2009