Assessment of a B-Mode Ultrasound Technique for the Measurement of Carotid Artery Intima-Media Thickness

This study has been completed.

Sponsored by:	National Institute of Allergy and Infectious Diseases (NIAID)
Information provided by:	National Institutes of Health Clinical Center (CC)
ClinicalTrials.gov Identifier:	NCT00001904

Purpose

This minimal risk protocol is designed to assess the reproducibility of B-mode ultrasound measurements of carotid intima media thickness (IMT) when the scans are performed in CC Radiology and read using a computerized edge reader. Up to 20 volunteers will have two ultrasounds performed within a 6-month period. IMT thickness is used as a surrogate marker for atherosclerosis and may be of value in clinical trials.

Condition
Atherosclerosis Myocardial Infarction

MedlinePlus related topics: Heart Attack Ultrasound

U.S. FDA Resources

Study Type:	Observational
Official Title:	Assessment of a B-Mode Ultrasound Technique for the Measurement of Carotid Artery Intima-Media Thickness

Further study details as provided by National Institutes of Health Clinical Center (CC):

Estimated Enrollment:	50
Study Start Date:	April 1999
Estimated Study Completion Date:	September 2000

Detailed Description:

This minimal risk protocol is designed to assess the reproducibility of B-mode ultrasound measurements of carotid intima-media thickness (IMT) when the scans are performed in CC Radiology and read using a computerized edge reader. Up to 50 volunteers will have two ultrasounds performed within a 6-month period. IMT thickness is used as a surrogate marker for atherosclerosis and may be of value in clinical trials.

Eligibility

Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	Yes

Criteria

Adult (age 18 or older).

Desire to participate in the study; willing and able to provide informed consent.

No history of stroke or carotid disease.

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00001904

Locations

United States, Maryland
National Institute of Allergy and Infectious Diseases (NIAID)
Bethesda, Maryland, United States, 20892

Sponsors and Collaborators

National Institute of Allergy and Infectious Diseases (NIAID)

More Information

Publications:

Tan GH, Gharib H. Thyroid incidentalomas: management approaches to nonpalpable nodules discovered incidentally on thyroid imaging. Ann Intern Med. 1997 Feb 1;126(3):226-31. Review.

Mercuri M. Noninvasive imaging protocols to detect and monitor carotid atherosclerosis progression. Am J Hypertens. 1994 Jul;7(7 Pt 2):23S-29S. Review.

Study ID Numbers:	990085, 99-I-0085
Study First Received:	November 3, 1999
Last Updated:	March 3, 2008
ClinicalTrials.gov Identifier:	NCT00001904
Health Authority:	United States: Federal Government

Keywords provided by National Institutes of Health Clinical Center (CC):

Atherosclerosis
Cardiovascular Disease
Computerized Edge Reader
Myocardial Infarction
Risk Factor

Study placed in the following topic categories:

Arterial Occlusive Diseases
Atherosclerosis
Necrosis
Heart Diseases
Myocardial Ischemia

Vascular Diseases
Ischemia
Arteriosclerosis
Infarction
Myocardial Infarction

Additional relevant MeSH terms:

Pathologic Processes
Cardiovascular Diseases

ClinicalTrials.gov processed this record on January 15, 2009