Dietary Approaches to Stop Hypertension (DASH) - Full Text View

Sponsored by:	National Heart, Lung, and Blood Institute (NHLBI)
Information provided by:	National Heart, Lung, and Blood Institute (NHLBI)
ClinicalTrials.gov Identifier:	NCT00000544

Purpose

To test the effectiveness of dietary patterns in lowering blood pressure.

Condition	Intervention	Phase
Cardiovascular Diseases Heart Diseases Hypertension Vascular Diseases	Behavioral: diet therapy	Phase III

MedlinePlus related topics: Heart Diseases High Blood Pressure Vascular Diseases

U.S. FDA Resources

Study Type:	Interventional
Study Design:	Treatment, Randomized

Further study details as provided by National Heart, Lung, and Blood Institute (NHLBI):

Study Start Date:	August 1993
Estimated Study Completion Date:	July 1997

Show Detailed Description

Eligibility

Ages Eligible for Study:	22 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Men and women with higher than optimal diastolic blood pressure or with Stage 1 (mild) hypertension.

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00000544

Sponsors and Collaborators

National Heart, Lung, and Blood Institute (NHLBI)

Investigators

Investigator:

William Vollmer

Kaiser Foundation Research Institute

More Information

Related Info This link exits the ClinicalTrials.gov site

Publications:

Laws R, Newgard ML. Bridging the gap: using ODBC to grab data stored in a SAS data warehouse for reporting in Microsoft Access. 21st Annual SAS Users Group 1996;724-728.

Sacks FM, Obarzanek E, Windhauser MM, Svetkey LP, Vollmer WM, McCullough M, Karanja N, Lin PH, Steele P, Proschan MA, et al. Rationale and design of the Dietary Approaches to Stop Hypertension trial (DASH). A multicenter controlled-feeding study of dietary patterns to lower blood pressure. Ann Epidemiol. 1995 Mar;5(2):108-18.

Appel LJ, Moore TJ, Obarzanek E, Vollmer WM, Svetkey LP, Sacks FM, Bray GA, Vogt TM, Cutler JA, Windhauser MM, Lin PH, Karanja N. A clinical trial of the effects of dietary patterns on blood pressure. DASH Collaborative Research Group. N Engl J Med. 1997 Apr 17;336(16):1117-24.

Appel LJ, Moore TJ, Obarzanek E. Dietary patterns and blood pressure. N Engl J Med 1997;337:637-638

Miller ER 3rd, Appel LJ, Jiang L, Risby TH. Association between cigarette smoking and lipid peroxidation in a controlled feeding study. Circulation. 1997 Aug 19;96(4):1097-101.

Vollmer WM, Svetkey LP, Appel LJ, Obarzanek E, Reams P, Kennedy B, Aicher K, Charleston J, Conlin PR, Evans M, Harsha D, Hertert S. Recruitment and retention of minority participants in the DASH controlled feeding trial. DASH Collaborative Research Group. Dietary Approaches to Stop Hypertension. Ethn Dis. 1998;8(2):198-208.

Zemel MB. Dietary pattern and hypertension: the DASH study. Dietary Approaches to Stop Hypertension. Nutr Rev. 1997 Aug;55(8):303-5. Review. No abstract available.

Blackburn GL. Functional foods in the prevention and treatment of disease: significance of the Dietary Approaches to Stop Hypertension Study. Am J Clin Nutr. 1997 Nov;66(5):1067-71. No abstract available.

Svetkey LP, Simons-Morton D, Vollmer WM, Appel LJ, Conlin PR, Ryan DH, Ard J, Kennedy BM. Effects of dietary patterns on blood pressure: subgroup analysis of the Dietary Approaches to Stop Hypertension (DASH) randomized clinical trial. Arch Intern Med. 1999 Feb 8;159(3):285-93.

Moore TJ, Vollmer WM, Appel LJ, Sacks FM, Svetkey LP, Vogt TM, Conlin PR, Simons-Morton DG, Carter-Edwards L, Harsha DW. Effect of dietary patterns on ambulatory blood pressure : results from the Dietary Approaches to Stop Hypertension (DASH) Trial. DASH Collaborative Research Group. Hypertension. 1999 Sep;34(3):472-7.

Windhauser MM, Ernst DB, Karanja NM, Crawford SW, Redican SE, Swain JF, Karimbakas JM, Champagne CM, Hoben KP, Evans MA. Translating the Dietary Approaches to Stop Hypertension diet from research to practice: dietary and behavior change techniques. DASH Collaborative Research Group. J Am Diet Assoc. 1999 Aug;99(8 Suppl):S90-5.

Plaisted CS, Lin PH, Ard JD, McClure ML, Svetkey LP. The effects of dietary patterns on quality of life: a substudy of the Dietary Approaches to Stop Hypertension trial. J Am Diet Assoc. 1999 Aug;99(8 Suppl):S84-9.

Windhauser MM, Evans MA, McCullough ML, Swain JF, Lin PH, Hoben KP, Plaisted CS, Karanja NM, Vollmer WM. Dietary adherence in the Dietary Approaches to Stop Hypertension trial. DASH Collaborative Research Group. J Am Diet Assoc. 1999 Aug;99(8 Suppl):S76-83.

Appel LJ, Vollmer WM, Obarzanek E, Aicher KM, Conlin PR, Kennedy BM, Charleston JB, Reams PM. Recruitment and baseline characteristics of participants in the Dietary Approaches to Stop Hypertension trial. DASH Collaborative Research Group. J Am Diet Assoc. 1999 Aug;99(8 Suppl):S69-75.

Phillips KM, Stewart KK, Karanja NM, Windhauser MM, Champagne CM, Swain JF, Lin PH, Evans MA. Validation of diet composition for the Dietary Approaches to Stop Hypertension trial. DASH Collaborative Research Group. J Am Diet Assoc. 1999 Aug;99(8 Suppl):S60-8.

Swain JF, Windhauser MM, Hoben KP, Evans MA, McGee BB, Steele PD. Menu design and selection for multicenter controlled feeding studies: process used in the Dietary Approaches to Stop Hypertension trial. DASH Collaborative Research Group. J Am Diet Assoc. 1999 Aug;99(8 Suppl):S54-9.

McCullough ML, Karanja NM, Lin PH, Obarzanek E, Phillips KM, Laws RL, Vollmer WM, O'Connor EA, Champagne CM, Windhauser MM. Comparison of 4 nutrient databases with chemical composition data from the Dietary Approaches to Stop Hypertension trial. DASH Collaborative Research Group. J Am Diet Assoc. 1999 Aug;99(8 Suppl):S45-53.

Lin PH, Windhauser MM, Plaisted CS, Hoben KP, McCullough ML, Obarzanek E. The Linear Index Model for establishing nutrient goals in the Dietary Approaches to Stop Hypertension trial. DASH Collaborative Research Group. J Am Diet Assoc. 1999 Aug;99(8 Suppl):S40-4.

Harsha DW, Lin PH, Obarzanek E, Karanja NM, Moore TJ, Caballero B. Dietary Approaches to Stop Hypertension: a summary of study results. DASH Collaborative Research Group. J Am Diet Assoc. 1999 Aug;99(8 Suppl):S35-9.

Karanja NM, McCullough ML, Kumanyika SK, Pedula KL, Windhauser MM, Obarzanek E, Lin PH, Champagne CM, Swain JF. Pre-enrollment diets of Dietary Approaches to Stop Hypertension trial participants. DASH Collaborative Research Group. J Am Diet Assoc. 1999 Aug;99(8 Suppl):S28-34.

Karanja NM, Obarzanek E, Lin PH, McCullough ML, Phillips KM, Swain JF, Champagne CM, Hoben KP. Descriptive characteristics of the dietary patterns used in the Dietary Approaches to Stop Hypertension Trial. DASH Collaborative Research Group. J Am Diet Assoc. 1999 Aug;99(8 Suppl):S19-27.

Vogt TM, Appel LJ, Obarzanek E, Moore TJ, Vollmer WM, Svetkey LP, Sacks FM, Bray GA, Cutler JA, Windhauser MM, Lin PH, Karanja NM. Dietary Approaches to Stop Hypertension: rationale, design, and methods. DASH Collaborative Research Group. J Am Diet Assoc. 1999 Aug;99(8 Suppl):S12-8. Review.

Obarzanek E, Moore TJ. Using feeding studies to test the efficacy of dietary interventions: lessons from the Dietary Approaches to Stop Hypertension trial. J Am Diet Assoc. 1999 Aug;99(8 Suppl):S9-11. No abstract available.

Sacks FM, Appel LJ, Moore TJ, Obarzanek E, Vollmer WM, Svetkey LP, Bray GA, Vogt TM, Cutler JA, Windhauser MM, Lin PH, Karanja N. A dietary approach to prevent hypertension: a review of the Dietary Approaches to Stop Hypertension (DASH) Study. Clin Cardiol. 1999 Jul;22(7 Suppl):III6-10.

Conlin PR, Chow D, Miller ER 3rd, Svetkey LP, Lin PH, Harsha DW, Moore TJ, Sacks FM, Appel LJ. The effect of dietary patterns on blood pressure control in hypertensive patients: results from the Dietary Approaches to Stop Hypertension (DASH) trial. Am J Hypertens. 2000 Sep;13(9):949-55.

Getchell WS, Svetkey LP, Appel LJ, Moore TJ, Bray GA, Obarzanek E. Summary of the Dietary Approaches to Stop Hypertension (DASH) Randomized Clinical Trial. Current treatment options in cardiovascular medicine.. 1999 Dec;1(4):295-300. No abstract available.

Obarzanek E, Sacks FM, Vollmer WM, Bray GA, Miller ER 3rd, Lin PH, Karanja NM, Most-Windhauser MM, Moore TJ, Swain JF, Bales CW, Proschan MA. Effects on blood lipids of a blood pressure-lowering diet: the Dietary Approaches to Stop Hypertension (DASH) Trial. Am J Clin Nutr. 2001 Jul;74(1):80-9.

Vollmer WM, Appel LJ, Svetkey LP, Moore TJ, Vogt TM, Conlin PR, Proschan M, Harsha D; DASH Collaborative Research Group. Comparing office-based and ambulatory blood pressure monitoring in clinical trials. J Hum Hypertens. 2005 Jan;19(1):77-82.

Study ID Numbers:	87
Study First Received:	October 27, 1999
Last Updated:	October 17, 2005
ClinicalTrials.gov Identifier:	NCT00000544
Health Authority:	United States: Federal Government

Study placed in the following topic categories:

Heart Diseases
Vascular Diseases
Hypertension

Additional relevant MeSH terms:

Cardiovascular Diseases

ClinicalTrials.gov processed this record on January 15, 2009