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Smoking Cessation in Alcoholism Treatment
This study has been completed.
Sponsored by: National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Information provided by: National Institute on Alcohol Abuse and Alcoholism (NIAAA)
ClinicalTrials.gov Identifier: NCT00000454
  Purpose

This study is designed to increase understanding of the processes that affect the treatment outcome of individuals with both alcohol and nicotine dependence. Treatment outcome methodology will be combined with a computerized self-monitoring methodology to examine the extent to which smoking serves as a cue for alcohol craving and/or as a response to alcohol craving in treated alcoholics. Subjects will be veterans participating in the Substance Abuse Day Programs at the Newington and West Haven campuses of the VA Connecticut Healthcare System. Nonveteran women will be recruited from the community and enrolled in the day program. Subjects will be randomly assigned to one of the following two conditions: (1) intensive smoking cessation therapy (counseling plus nicotine replacement using nicotine patches) concurrent with alcohol treatment, or (2) brief smoking cessation advice concurrent with alcohol treatment.


Condition Intervention Phase
Alcoholism
Smoking
Drug: nicotine replacement patch
Phase IV

MedlinePlus related topics: Alcoholism Quitting Smoking Smoking
Drug Information available for: Nicotine polacrilex Nicotine tartrate
U.S. FDA Resources
Study Type: Interventional
Study Design: Treatment, Randomized, Open Label, Efficacy Study
Official Title: Field Study of Smoking Cessation in Alcoholism Treatment

Further study details as provided by National Institute on Alcohol Abuse and Alcoholism (NIAAA):

Estimated Enrollment: 112
Estimated Study Completion Date: August 2002
  Eligibility

Ages Eligible for Study:   21 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Meets criteria for alcohol dependence within the past three months, and criteria for nicotine dependence.
  • Smoking at least 10 or more cigarettes per day for the past year.
  • Seeking treatment for both alcohol and nicotine dependence.
  • Minimum 1 week of alcohol abstinence and substance abuse day treatment attendance.
  • Willing to provide names of two individuals who can help locate the subject at follow-up.
  • Willing to provide name of one individual who can provide collateral information about alcohol and tobacco use.

Exclusion Criteria:

  • Other substance use disorder meeting criteria for dependence.
  • Acute medical or psychiatric disorder requiring inpatient treatment.
  • Taking medications known to influence alcohol urges (naltrexone, disulfiram).
  • Medical problems that would contraindicate nicotine patch use.
  • Allergy or hypersensitivity to nicotine or to adhesives used in transdermal delivery systems.
  • Use of other nicotine products such as cigars, pipes, or smokeless tobacco.
  • Severe generalized skin disorder.
  • Myocardial infarction within 3 months prior to study entry.
  • Unstable angina.
  • Pregnant or lactating females, or females who are not practicing a medically accepted form of contraception.
  • Impaired vision or hearing which would interfere with using a hand-held computer.
  • Reading ability below fifth grade level.
  • Lack of reliable transportation to the treatment site, or living more than 1 hour from treatment site.
  • Homeless or unstable residence.
  • Plan for future admission to residential treatment.
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00000454

Locations
United States, Connecticut
Substance Abuse Treatment Center, VA Medical Center
West Haven, Connecticut, United States, 06516
Sponsors and Collaborators
  More Information

Study ID Numbers: NIAAACOO11197
Study First Received: November 2, 1999
Last Updated: June 23, 2005
ClinicalTrials.gov Identifier: NCT00000454  
Health Authority: United States: Federal Government

Study placed in the following topic categories:
Nicotine polacrilex
Smoking
Nicotine
Mental Disorders
Alcoholism
Substance-Related Disorders
Disorders of Environmental Origin
Alcohol-Related Disorders

Additional relevant MeSH terms:
Habits

ClinicalTrials.gov processed this record on January 15, 2009