Full Text View  
  Tabular View  
  Contacts and Locations  
  No Study Results Posted  
  Related Studies  
Effects of Subanesthetic Concentrations of Isoflurane/Nitrous Oxide - 3
This study has been completed.
Sponsors and Collaborators: National Institute on Drug Abuse (NIDA)
University of Chicago
Information provided by: National Institute on Drug Abuse (NIDA)
ClinicalTrials.gov Identifier: NCT00000251
  Purpose

The purpose of this study is to conduct experiments to examine subjective and reinforcing effects of nitrous oxide. Mood altering and psychomotor effects will be tested on non-drug abusers and preference procedures will be used to assess reinforcing effects. Comparisons between nitrous oxide, opiates, and benzodiazepine antagonists will be made. To evaluate the acute and residual effects of subanesthetic concentrations of isoflurane/nitrous oxide combinations in healthy volunteers.


Condition Intervention Phase
Opioid-Related Disorders
Substance-Related Disorders
Drug: Nitrous oxide
Phase II

Drug Information available for: Isoflurane Nitrous oxide
U.S. FDA Resources
Study Type: Interventional
Study Design: Treatment
Official Title: Effects of Subanesthetic Concentrations of Isoflurane/Nitrous Oxide

Further study details as provided by National Institute on Drug Abuse (NIDA):

Primary Outcome Measures:
  • Psychomotor performance
  • Cognitive performance

Estimated Enrollment: 0
Study Start Date: April 1994
  Eligibility

Ages Eligible for Study:   21 Years to 32 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Please contact site for information.

  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00000251

Locations
United States, Illinois
University of Chicago, Anesthesia & Critical Care
Chicago, Illinois, United States, 60637
Sponsors and Collaborators
University of Chicago
Investigators
Principal Investigator: James Zacny, Ph.D. University of Chicago
  More Information

Study ID Numbers: NIDA-08391-3, R01-08391-3
Study First Received: September 20, 1999
Last Updated: November 3, 2005
ClinicalTrials.gov Identifier: NCT00000251  
Health Authority: United States: Federal Government

Study placed in the following topic categories:
Mental Disorders
Nitrous Oxide
Isoflurane
Substance-Related Disorders
Disorders of Environmental Origin
Opioid-Related Disorders

Additional relevant MeSH terms:
Disease
Physiological Effects of Drugs
Anesthetics
Central Nervous System Depressants
Pharmacologic Actions
Anesthetics, Inhalation
Pathologic Processes
Anesthetics, General
Analgesics, Non-Narcotic
Sensory System Agents
Therapeutic Uses
Peripheral Nervous System Agents
Analgesics
Central Nervous System Agents

ClinicalTrials.gov processed this record on January 15, 2009