IV Cocaine Abuse: A Laboratory Model - 3

This study has been completed.

Sponsors and Collaborators:	National Institute on Drug Abuse (NIDA) Columbia University
Information provided by:	National Institute on Drug Abuse (NIDA)
ClinicalTrials.gov Identifier:	NCT00000214

Purpose

The purpose of this study is to evaluate the effects of buprenorpine on cocaine taking and on the physiological and subjective effects of cocaine, including cocaine craving in non-opiate dependent cocaine users.

Condition	Intervention	Phase
Cocaine-Related Disorders	Drug: Buprenorphine	Phase II

Drug Information available for: Buprenorphine Buprenorphine hydrochloride 8-Azabicyclo(3.2.1)octane-2-carboxylic acid, 3-(benzoyloxy)-8-methyl-, methyl ester, (1R-(exo,exo))- Cocaine hydrochloride

U.S. FDA Resources

Study Type:	Interventional
Study Design:	Treatment
Official Title:	IV Cocaine Abuse: A Laboratory Model

Further study details as provided by National Institute on Drug Abuse (NIDA):

Primary Outcome Measures:

Direct cocaine effects (caridio, subjective)
Interaction of coc/bup on cardio measures
Ineraction of coc/bup on coc's subjective effects
Effects of buprenorphine on cocaine craving

Estimated Enrollment:	0
Study Start Date:	January 1992

Eligibility

Ages Eligible for Study:	18 Years to 45 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Please contact site for information.

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00000214

Locations

United States, New York
Columbia University
New York, New York, United States, 10023

Sponsors and Collaborators

National Institute on Drug Abuse (NIDA)

Columbia University

Investigators

Principal Investigator:

Richard Foltin, Ph.D.

Columbia University

More Information

Study ID Numbers:	NIDA-06234-3, R01-06234-3
Study First Received:	September 20, 1999
Last Updated:	June 23, 2005
ClinicalTrials.gov Identifier:	NCT00000214
Health Authority:	United States: Federal Government

Study placed in the following topic categories:

Cocaine-Related Disorders
Buprenorphine
Mental Disorders

Substance-Related Disorders
Disorders of Environmental Origin
Cocaine

Additional relevant MeSH terms:

Sensory System Agents
Therapeutic Uses
Narcotic Antagonists
Physiological Effects of Drugs
Central Nervous System Depressants
Narcotics

Peripheral Nervous System Agents
Analgesics
Central Nervous System Agents
Pharmacologic Actions
Analgesics, Opioid

ClinicalTrials.gov processed this record on January 15, 2009