IV Cocaine Abuse: A Laboratory Model - 2

This study has been completed.

Sponsors and Collaborators:	National Institute on Drug Abuse (NIDA) Columbia University
Information provided by:	National Institute on Drug Abuse (NIDA)
ClinicalTrials.gov Identifier:	NCT00000213

Purpose

The purpose of this study is to evaluate the effects of fluoxetine maintenance on cocaine taking and on the physiological and subjective effects of cocaine, including cocaine craving.

Condition	Intervention	Phase
Cocaine-Related Disorders	Drug: Fluoxetine	Phase II

Drug Information available for: Fluoxetine 8-Azabicyclo(3.2.1)octane-2-carboxylic acid, 3-(benzoyloxy)-8-methyl-, methyl ester, (1R-(exo,exo))- Cocaine hydrochloride Fluoxetine hydrochloride

U.S. FDA Resources

Study Type:	Interventional
Study Design:	Treatment
Official Title:	IV Cocaine Abuse: A Laboratory Model

Further study details as provided by National Institute on Drug Abuse (NIDA):

Primary Outcome Measures:

Direct cocaine effects
Interaction of cocaine/fluox. on cardio measures
Interaction of cocaine/fluox. on coc's subjective
Effects of fluoxetine on cocaine craving
Drug use during outpatient fluoxetine maintenance

Estimated Enrollment:	0
Study Start Date:	April 1990

Eligibility

Ages Eligible for Study:	18 Years to 45 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Please contact site for information.

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00000213

Locations

United States, New York
Columbia University
New York, New York, United States, 10023

Sponsors and Collaborators

National Institute on Drug Abuse (NIDA)

Columbia University

Investigators

Principal Investigator:

Richard Foltin, Ph.D.

Columbia University

More Information

Study ID Numbers:	NIDA-06234-2, R01-06234-2
Study First Received:	September 20, 1999
Last Updated:	June 23, 2005
ClinicalTrials.gov Identifier:	NCT00000213
Health Authority:	United States: Federal Government

Study placed in the following topic categories:

Fluoxetine
Cocaine-Related Disorders
Mental Disorders
Substance-Related Disorders

Disorders of Environmental Origin
Cocaine
Serotonin

Additional relevant MeSH terms:

Neurotransmitter Agents
Neurotransmitter Uptake Inhibitors
Serotonin Agents
Molecular Mechanisms of Pharmacological Action
Therapeutic Uses
Physiological Effects of Drugs

Psychotropic Drugs
Antidepressive Agents, Second-Generation
Central Nervous System Agents
Serotonin Uptake Inhibitors
Antidepressive Agents
Pharmacologic Actions

ClinicalTrials.gov processed this record on January 15, 2009