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Body Water Content in Cyanotic Congenital Heart Disease
This study has been completed.
Sponsored by: National Center for Research Resources (NCRR)
Information provided by: National Center for Research Resources (NCRR)
ClinicalTrials.gov Identifier: NCT00000107
  Purpose

Adults with cyanotic congenital heart disease have elevated levels of plasma proatrial natruretic peptide (proANP) which most likely results in chronic dehydration, leading to reduced oxygen transport to tissues and shortness of breath with activity. The purpose of this study is to characterize adults with cyanotic congenital heart defects with respect to their body composition (water and fat-free mass) and resting metabolic rates. The study consists of several measures of how much body water, fat and lean tissue a subject has, and measures the number of calories the subject's body uses at rest. Adult subjects with cyanotic congenital heart disease will be recruited along with healthy noncyanotic control subjects matched for age, gender, and body weight.


Condition
Heart Defects, Congenital

MedlinePlus related topics: Congenital Heart Defects Drinking Water Heart Diseases
U.S. FDA Resources
Study Type: Observational
Study Design: Natural History, Case Control
  Eligibility

Ages Eligible for Study:   17 Years to 60 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Resting blood pressure below 140/90
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00000107

Locations
United States, Vermont
University of Vermont
Burlington, Vermont, United States, 05401
Sponsors and Collaborators
  More Information

Study ID Numbers: NCRR-M01RR00109-0737, M01RR00109
Study First Received: January 18, 2000
Last Updated: June 23, 2005
ClinicalTrials.gov Identifier: NCT00000107  
Health Authority: United States: Federal Government

Keywords provided by National Center for Research Resources (NCRR):
Cyanotic Congenital Heart Disease

Study placed in the following topic categories:
Heart Diseases
Cardiovascular Abnormalities
Congenital Abnormalities
Heart Defects, Congenital

Additional relevant MeSH terms:
Cardiovascular Diseases

ClinicalTrials.gov processed this record on January 15, 2009