Tissue-Specific Mechanisms Regulating Inflammation-Associated Epithelial Carcinogenesis (NIH-Only)

 


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Air date: Tuesday, June 24, 2008, 8:00:00 AM
Category: NCI CCR Grand Rounds (NIH Only)
Runtime: 60 minutes
NLM Title: Tissue-specific mechanisms regulating inflammation-associated epithelial carcinogenesis [electronic resource] / Lisa M. Coussens.
Series: CCR grand rounds
Author: Coussens, Lisa M.
National Institutes of Health (U.S.)
Publisher: [Bethesda, Md. : National Institutes of Health, 2008]
Other Title(s): CCR grand rounds
Abstract: (CIT): Dr. Coussens received her B.A. in Biology at San Francisco State University. She then worked as a research associate in molecular and developmental biology at Genentech, Inc., in S. San Francisco for 7 years before pursuing her Ph.D. in biological chemistry from the University of California, Los Angeles, followed by postdoctoral studies in cancer biology at the University of California, San Francisco (UCSF). Dr. Coussens joined the Cancer Research Institute and Dept. of Pathology at UCSF where she is currently a professor. The Coussens lab focuses on the role of immune cells and leukocyte proteases as critical regulators of skin, lung, and breast cancer development where they are investigating mechanisms involved in the: i. induction and maintenance of chronic inflammatory microenvironments in premalignant tissues, ii. role of leukocyte proteases as regulators of tissue remodeling, angiogenesis and cancer development, and iii. development of novel non-invasive imaging reagents to monitor inflammation in tissues. The lab"s studies are designed to test the hypothesis that inflammation is a critical parameter of neoplastic development and therefore represents an efficacious target for anti-cancer therapy. Dr. Coussens has served on editorial boards for peer-reviewed journals and is currently the deputy editor for Cancer Research. Her laboratory has published numerous articles, abstracts, and book chapters and she routinely speaks at national and international conferences. The primary educational objective of these seminars is to provide new information, ideas, and discussion about timely areas of research with impact on the field of oncology. A secondary educational objective is to elicit participation by individuals from all divisions of the intramural NCI, and thus facilitate more interactions among investigators and groups in the NCI.
Subjects: Inflammation
Neoplasm Metastasis--immunology
Neoplasms, Glandular and Epithelial--immunology
Publication Types: Government Publications
Lectures
NLM Classification: QZ 365
NLM ID: 101478265
CIT File ID: 14573
CIT Live ID: 6845
Permanent link: http://videocast.nih.gov/launch.asp?14573