Last Update: 08/16/2006 Printer Friendly Printer Friendly   Email This Page Email This Page  

Collaborative Home Infant Monitoring Evalutation (CHIME)

CHIMEThe CHIME Study, now complete, was a multicenter, cooperative study of home monitoring of high-risk infants supported by the Pregnancy and Perinatology Branch. Almost 1,200 infants were enrolled in the following subject groups: healthy term infants; preterm infants weighing less than 1,750 grams; and siblings babies who died of SIDS or experienced an idiopathic apparent life-threatening event. The objectives of the study were to:

  • Determine whether home apnea monitors that employed event recordings were effective in identifying episodes dangerous to infant health
  • Determine the conditions that optimized the use of apnea monitors in high-risk infants
  • Correlate physiological markers, health status, and behavior with the propensity for life-threatening events
  • Provide important information on the maturation of heart and respiratory functions in sleeping infants

The CHIME database, which includes all raw physiological records and study forms was recently transferred to CD-ROM; in January 2004, the entire database became accessible to researchers at http://dccwww.bumc.bu.edu/ChimeNisp/.