Biography

Dr. Mbulaiteye received his M.D. from Makerere University, Kampala, in 1990, an MPhil in Epidemiology and Biostatistics from Cambridge University in 1994 and a Masters in Internal Medicine from Makerere University in 1996. He worked as a Senior Registrar at the Uganda Cancer Institute and a Project Medical Officer in the Medical Research Council Programme for AIDS in Uganda before joining NCI as a Research Fellow in 2000. He became a tenure-track investigator in 2005. He is a member of the Uganda National Academy of Sciences, the African Organization for Research and Training in Cancer (AORTIC), Darwin College Society, and Cambridge Common Wealth Trust. Currently, he is serves on the DCEG Technical Evaluation of Questionnaires and Technical Evaluation of Protocols committees, and is an adjunct lecturer at George Washington University School of Public Health.

Research Interests

• Human γ-herpesviruses, human herpesvirus 8 (HHV-8) and Epstein-Barr virus (EBV), and their associated cancers--Kaposi sarcoma, primary effusion lymphoma and Burkitt lymphoma, respectively
• Immunosuppression or immune alteration and their relationship to cancer etiology and/or pathogenesis in diverse populations
• Co-factors for uniquely distributed cancers, such as gastric cancer and oral cancers, which have distinct but unexplained distributions in different populations

Keywords

Human herpesvirus 8 (HHV-8), Epstein-Barr virus, Kaposi sarcoma, lymphoma, AIDS, immunosuppression, chimerism, gastric cancer, epidemiology, genetic risk, Africa

Selected Publications

• Mbulaiteye SM, Marshall V, Bagni RK, Wang C, Mbisa G, Bakaki PM, Owor AM, Ndugwa CM, Engels EA, Katongole-Mbidde E, Biggar RJ and Whitby D. Molecular Evidence for Mother to Child Transmission of Kaposi’s Sarcoma Associated Herpesvirus (KSHV) In Uganda and K1 Gene Evolution within the Host. J Infect Dis 2006; 193:1250-7.
• Mbulaiteye, S.M., Katabira, E. T., Wabinga, H., Parkin, D. M., Virgo, P., Ochai, R., Workneh, M., Coutinho, A., and Engels, E. A. Spectrum of cancers among HIV-infected persons in Africa: the Uganda AIDS-Cancer Registry Match Study. Int J Cancer 2006; 118: 985-990.
• Nawar, E., Mbulaiteye, S. M., Gallant, J. E., Wohl, D. A., Ardini, M., Hendershot, T., Goedert, J. J., and Rabkin, C. S. Risk factors for Kaposi's sarcoma among HHV-8 seropositive homosexual men with AIDS. Int J Cancer 2005; 115: 296-300.
• Mbulaiteye, S. M., Pfeiffer, R. M., Engels, E. A., Marshall, V., Bakaki, P. M., Owor, A. M., Ndugwa, C. M., Katongole-Mbidde, E., Goedert, J. J., Biggar, R. J., and Whitby, D. Detection of Kaposi sarcoma-associated herpesvirus DNA in saliva and buffy-coat samples from children with sickle cell disease in Uganda. J Infect Dis 2004; 190: 1382-1386.
• Mbulaiteye, S. M., Biggar, R. J., Bakaki, P. M., Pfeiffer, R. M., Whitby, D., Owor, A. M., Katongole-Mbidde, E., Goedert, J. J., Ndugwa, C. M., and Engels, E. A. Human herpesvirus 8 infection and transfusion history in children with sickle-cell disease in Uganda. J Natl Cancer Inst 2003; 95: 1330-1335.
• Eltom, M. A., Jemal, A., Mbulaiteye, S. M., Devesa, S. S., and Biggar, R. J. Trends in Kaposi's sarcoma and non-Hodgkin's lymphoma incidence in the United States from 1973 through 1998. J Natl Cancer Inst 2002; 94: 1204-1210.

Collaborators

DCEG Collaborators

• Eric A. Engels, M.D., Anil Chaturvedi, Ph.D., Charles S. Rabkin, M.D., James J. Goedert, M.D., Ruth M. Pfeiffer, Ph.D. Denise Whitby, Ph.D., Michie Hisada, M.D., Dsc., Andrew Bergen, Ph.D, Steven Chanock, M.D.

Other NCI Collaborators

• Jim Taylor, M.D., Paul Meltzer, M.D., Bob Walker, M.D.

Other Scientific Collaborators

• Victor Tsang, Ph.D., Centers for Disease Control and Prevention, Atlanta, GA
• Benjamin D. Gold, M.D., University of Emory, Atlanta, GA
• Thomas Strickland, M.D., University of Maryland, MD
• Mohammed R. Moosa, M.D., University of Stellenbosch, Cape Town, South Africa
• Johann Schneider, M.D., University of Stellenbosch, Cape Town, South Africa
• Glen R. Brubaker, M.D., Interchurch Mission/Shirati Hospital, Tanzania
• John Shao, M.D., Kilimanjaro Christian Medical Center/Shirati Hospital, Tanzania
• Martin D. Ogwang, St. Mary’s Hospital, Lacor, Gulu, Uganda
• Henry Wabinga, MB ChB, Kampala Cancer Registry, Kampala, Uganda
• Martin M. Nsubuga, MRCP, Nsambya Hospital, Kampala, Uganda
• Elly Katabira, MRCP, Makerere University, Kampala, Uganda
• Ajay Sethi, Ph.D., Case Western Reserve University, Cleveland, OH
• Aruna Alahaari, M.D., Tata Memorial Center, Mumbai, India
• Maxwell D. Parkin, M.D. Oxford University, UK
• Robert J. Biggar, M.D. Staten Serum Institute, Copenhagen, Denmark