NINDS Dyssynergia Cerebellaris Myoclonica Information Page

Synonym(s):   Dyssynergia Cerebellaris Progressiva, Dentate Cerebellar Ataxia, Dentatorubral Atrophy, Primary Dentatum Atrophy, Ramsay Hunt Syndrome I (formerly known as)

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What is Dyssynergia Cerebellaris Myoclonica?

Dyssynergia Cerebellaris Myoclonica refers to a collection of rare, degenerative, neurological disorders characterized by epilepsy, cognitive impairment, myoclonus, and progressive ataxia.  Symptoms include seizures, tremor, and reduced muscle coordination.  Onset of the disorder generally occurs in early adulthood.  Tremor may begin in one extremity and later spread to involve the entire voluntary muscular system.  Arms are usually more affected than legs.  Some of the cases are due to mitochondrial abnormalities.

Is there any treatment?

What is the prognosis?

What research is being done?

NIH Patient Recruitment for Dyssynergia Cerebellaris Myoclonica Clinical Trials

• At NIH Clinical Center
• Throughout the U.S. and Worldwide

Organizations

National Institute on Deafness and Other Communication Disorders (NIDCD) National Institutes of Health, DHHS 31 Center Drive, MSC 2320 Bethesda, MD   20892-2320 nidcdinfo@nidcd.nih.gov http://www.nidcd.nih.gov Tel: 301-496-7243/800-241-1044 800-241-1055 (TTD/TTY)	National Ataxia Foundation (NAF) 2600 Fernbrook Lane North Suite 119 Minneapolis, MN   55447-4752 naf@ataxia.org http://www.ataxia.org Tel: 763-553-0020 Fax: 763-553-0167
National Organization for Rare Disorders (NORD) P.O. Box 1968 (55 Kenosia Avenue) Danbury, CT   06813-1968 orphan@rarediseases.org http://www.rarediseases.org Tel: 203-744-0100 Voice Mail 800-999-NORD (6673) Fax: 203-798-2291

Prepared by:
Office of Communications and Public Liaison
National Institute of Neurological Disorders and Stroke
National Institutes of Health
Bethesda, MD 20892

NINDS health-related material is provided for information purposes only and does not necessarily represent endorsement by or an official position of the National Institute of Neurological Disorders and Stroke or any other Federal agency. Advice on the treatment or care of an individual patient should be obtained through consultation with a physician who has examined that patient or is familiar with that patient's medical history.

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Last updated February 12, 2007