The National Cancer Institute (NCI) invites grant applications (P50) for NIH-Supported Centers for Population Health and Health Disparities (CPHHD II): RFA-CA-09-001
This funding opportunity announcement (FOA), sponsored jointly by the National Cancer Institute (NCI), the National Heart, Lung and Blood Institute (NHLBI), and Office of Behavioral and Social Sciences (OBSSR) of the National Institutes of Health, solicits grant applications for Centers for Population Health and Health Disparities (CPHHD) Program. The CPHHD Program is designed to promote transdisciplinary research in the area of health inequities with the purpose of contributing directly to improved health outcomes and quality of life for populations with a higher disease burden. This FOA is an open competition for all eligible applicants. The focus is on both understanding the pathways that result in disparate health outcomes and developing comprehensive models of how various social, economic, cultural, environmental, biological, behavioral, physiological, and genetic factors affect individual health outcomes and their distribution in populations. Under this FOA, the National Cancer Institute (NCI) will support centers focused on health disparities related to the differences in the incidence, prevalence, mortality, and burden of cancer and related adverse health conditions that exist among specific population groups in the United States (U.S.). Centers proposed for funding by the NHLBI must target disparities in cardiovascular diseases and must have the development of interventions to reduce these health disparities as the primary objective of the proposed research. Applicants proposing Centers focused on cancer-related disparities are must include intervention development/testing as one of required projects. Ultimately, for both areas, the results of the proposed research should aid the development of effective strategies for multilevel interventions to that seek to promote health and/or lessen the burden of disease.
In September 2003, the National Institutes of Health (NIH) established eight Centers for Population Health and Health Disparities, designed to support cutting-edge research to understand and reduce differences in health outcomes, access and care. Four NIH institutes or offices the National Institute of Environmental Health Sciences (NIEHS), the National Cancer Institute (NCI), the National Institute on Aging (NIA), and the Office of Behavioral and Social Sciences Research (OBSSR) ? are supporting this interdisciplinary research to examine how the social and physical environment, behavioral factors, and biologic pathways interact to determine health and disease in populations.
These grants, which total $60.5 million over five years, address the recommendations of recent reports from the National Academy of Sciences. The reports called for an approach to health and health disparities that integrates research in the natural, behavioral and social sciences to create a more comprehensive understanding of disease pathways. The reports also stressed the need to examine causation and intervention at the population and environmental levels, rather than solely at the individual level. Based upon these reports and other sources, the participating NIH units issued a Request for Applications (RFA) on April 1, 2002: RFA ES-02-009, Centers for Population Health and Health Disparities.
In announcing the formation of the centers, DHHS Secretary Thompson emphasized ?It is vital that all populations benefit from scientific knowledge and advances...This initiative is an exciting step toward understanding and eliminating health disparities for numerous diseases throughout the United States.
The eight centers form a network of research teams to explore the complexity of health disparities. Investigators are following a community-based research approach that involves community stakeholders in the planning and implementation of research, with studies focusing on obesity, cardiovascular disease, breast cancer, prostate cancer, cervical cancer, mental health, gene-environment interactions, psychosocial stress, and other factors. Populations will include low-income whites, African Americans, Hispanics, and the elderly.
"Today, people in this country of various backgrounds, ages, or socioeconomic levels bear an unequal burden of disease," said NIH Director Elias A. Zerhouni. "These centers will perform innovative research, collaborating extensively to address the important and complicated issue of health disparities."
Total initiative amount: $60.5 million
NCI – $6.5M per year over 5 years = $32.5 M
NIEHS – $4.0M per year over 5 years = $20 M
NIA – $1.6M per year over 5 years = $8 M