Testing Information

Descriptions of NTP Study Types

Teratology Abstracts

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Inhalation Developmental Toxicology Studies: Teratology Studies of Acetone (CAS No. 67-64-1) in Swiss (CD-1®) Mice and Sprague-Dawley Rats

Inhalation Development Toxicology Studies: Acetonitrile (CAS No.75-05-8) in Sprague-Dawley Rats

Teratologic Evaluation of Acrylamide (CAS NO-. 791-06-1) Administered to Sprague-Dawley (CD) Rats on Gestational Days 6 through 20

Teratologic Evaluation of Acrylamide (CAS No.79-06-1) Administered to CD-1 (Swiss Mice) on Gestational Days 6 through 17

Arsine (CAS No. 7784-42-1): Absence of Developmental Toxicity in Rats and Mice (Morrissey RE, Fowler BA, Harris MW, Moorman MP, Jameson CW, Schwetz BA. Arsine: Absence of Developmental Toxicity in Rats and Mice. FAAT. 15(2):350-356. (1990))

Developmental Toxicity Evaluation of 3'-Azido-3'-deoxythymidine and 2', 3'-Dideoxycytidine (AZT; CAS No. 30516-87-1 ddC; CAS No. 7481-89-2) Administered by Gavage to Swiss Albino (CD-1®) Mice on Gestational Days 6-15

Developmental Toxicity Evaluation of 3'-Azido-3'-deoxythymidine (AZT; CAS No. 30516-87-1) and (-) 2', 3'-Dideoxy-3'-thiacytidine (3TC; CAS No. 134678-17-4) Co-administered by Gavage to Swiss Albino (CD-1®) Mice on Gestational Days 6 Through 16

Developmental Toxicity Evaluation of 3'-Azido-3'-deoxythymidine (AZT; CAS No. 30516-87-1) and Dapsone (CAS No. 80-08-0) Administered by Gavage to Swiss Albino (CD-1®) Mice on Gestational Days 6 Through 15

Teratologic Evaluation of Bendectin (CAS No. 8064-77-5), in Sprague-Dawley (CD®) Rats

Developmental Toxicity Evaluation for Benzophenone (CAS No. 119-61-9) Administered by Gavage to Sprague-Dawley (CD®) Rats on Gestational Days 6 through 19

Developmental Toxicity Evaluation for Benzophenone (CAS No. 119-61-9) Administered by Gavage to New Zealand White Rabbits on Gestational Days 6 through 29

Developmental Toxicity Evaluation of Berberine Chloride Dihydrate (CAS NO. 5956-60-5) Administered in the Feed to Swiss (CD-1®) Mice on Gestational Days 6 to 17

Developmental Toxicity Evaluation for Berberine Chloride Dihydrate (CAS No. 5956-60-5) Administered in the Feed to Sprague-Dawley (CD®) Rats on Gestational Days 6 to 20

Developmental Toxicity Research Evaluation for Berberine Chloride Dihydrate (CAS No. 5956-60-5) Administered by Gavage to Sprague-Dawley (CD®) Rats on Gestational Days 6 through 19

Developmental Toxicity Research Evaluation for Berberine Chloride Dihydrate (CAS No. 5956-60-5) Administered by Gavage to Swiss (CD-1®) Mice on Gestational Days 6 through 16

Teratologic Evaluation of Bisphenol A (CAS No. 80-05-7) Administered to CD® Rats on Gestational Days 6 through 15

Teratologic Evaluation of Bisphenol A (CAS No. 80-05-7), in CD-1 Mice on Gestational Days 6 through 15

Developmental Toxicity of Boric Acid (CAS No. 10043-35-3) Administered in Feed to Sprague-Dawley (CD) Rats on Gestational Days 0 to 20 or 6 to 15

Evaluation of CNS Development in Sprague-Dawley CD® Rats Exposed to Boric Acid (CAS No. 10043-35-3) in Feed on Gestational Days 14-17

CNS Developmental Toxicity of Boric Acid (CAS No. 10043-35-3) in Sprague-Dawley CD® Rats Exposed on Gestation Days 6-15

Developmental Toxicity Evaluation of Boric Acid (CAS No. 10043-35-3) Administered in Feed to CD-1® Swiss Mice on Gestational Days 0 to 17

Developmental Toxicity Evaluation of Boric Acid (Cas No. 10043-35-3) Administered to New Zealand White Rabbits by Gavage on Gestational Days 6 through 19

Inhalation Developmental Toxicology Studies of 1,3-Butadiene (CAS No. 106-99-0) in Sprague-Dawley Rats

Inhalation Developmental Toxicology Studies: Teratology Study of 1,3-Butadiene (CAS No.106-99-0) in CD-1® Mice

Inhalation Developmental Toxicology Studies: Teratology Study of 1,4-Butanediol (CAS No. 110-63-4), in Swiss (CD-1®) Mice

Developmental Toxicity Evaluation for 1,2,3,4-Butanetetracarboxylic Acid (CAS No. 1703-58-8) Administered by Gavage to Sprague-Dawley (CD®) Rats from Gestational Day 6 Through 19

Butyl Benzyl Phthalate (CAS No. 85-68-7), in CD-1 Mice

Butyl Benzyl Phthalate (CAS No. 85-68-7), in Sprague-Dawley Rats

d-Camphor (CAS No. 464-49-3), in CD Rats

d-Camphor (CAS No. 464-49-3), in Rabbits

Carbon Disulfide (CAS No. 75-15-0), in CD Rats

Carbon Disulfide (CAS No. 75-15-0), in New Zealand White rabbits

Chloroprene (CAS No. 126-99-8), in New Zealand White Rabbits

Chlorpromazine Hydrochloride (CAS No. 69-09-0), in F/344 Rats

Chlorpromazine Hydrochloride (CAS No. 69-09-0), in CD-1 mice

Codeine (CAS No. 76-57-3), in CD-1 Mice

Codeine (CAS No. 76-57-3), in LVG Hamsters

a-Cyclodextrin (CAS No. 10016-20-3) , in Sprague-Dawley (CD®) Rats

a-Cyclodextrin (CAS No. 10016-20-3), in Swiss (CD-1) Mice

2,4-dichiorophenoxyacetic acid (2,4-D), 2,4,5-trichlorophenoxyacetic acid (2,4,5-T), and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) (NTP CAS No. AGNTORANGEMX) in C57BL/6 mice

2',3'-Dideoxyinosine (ddI; CAS No. 69655-05-6) and 2',3'-Didehydro-3'-Deoxythymidine (d4T; CAS No. 3056-17-5) Co-administered by Gavage to Swiss Albino (CD-1®) Mice on Gestational Days 6 Through 16

Diethanolamine (CAS No. 111-42-2), in Sprague-Dawley (CD®) Rats

Diethyl Phthalate (CAS No. 84-66-2), in CD Rats

Diethylene Glycol (CAS No. 111-46-6), in CD-1 Mice

Diethylene Glycol Diethyl Ether (CAS No.112-36-7), in CD-1 Mice

Diethylene Glycol Diethyl Ether (CAS No. 112-36-7), in New Zealand White Rabbits

Diethylene Glycol Dimethyl Ether (CAS No. 111-96-6), in CD-1®Mice

Diethylene Glycol Dimethyl Ether (CAS No. 111-96-6), in New Zealand White Rabbits

Diethylhexyl Phthalate (CAS No. 117-81-7), in Fischer 344 Rats

Diethylhexyl Phthalate (CAS No. 117-81-7), in CD-1® Mice

Diethylstilbestrol (CAS NO. 56-53-1) in Swiss (CD-1)Mice

Dimethyl Phthalate (CAS No. 131-11-3), in CD Rats

Diphenhydramine Hydrochloride (CAS No. 147-24-0), in CD® Rats

Diphenhydramine Hydrochloride (CAS No. 147-24-0), in CD-1 Mice [gd 11 through 14]

Diphenhydramine Hydrochloride (CAS No. 147-24-0), in CD-1 Mice [gd 6 through 15]

Dipropylene Glycol (CAS No. 25265-71-8), in Sprague-Dawley (CD®) Rats

Dipropylene Glycol (CAS No. 25265-71-8), in New Zealand White Rabbits

Emodin (CAS No. 518-82-1), in Sprague-Dawley (CD) Rats [gd 6 to 20]

Emodin (CAS No. 518-82-1), in Swiss Mice (CD-1®) [gd 6 to 17]

Ethylene Chlorohydrin (CAS No. 107-07-3), in CD-1 Mice

Ethylene Chlorohydrin (CAS No. 107-07-3), in New Zealand White rabbits

Ethylene Glycol (CAS No. 107-21-1), in CD-1 Mice

Ethylene Glycol (CAS No. 107-21-1), in CD Rats

Ethylene Glycol (CAS No 107-21-1), in New Zealand White Rabbits

Ethylene Glycol (CAS No. 107-21-1); Developmental Stages of the CD® Rat Skeleton : Part II: Development after Maternal Exposure to Ethylene Glycol

Ethylene Glycol Diethyl Ether (CAS No. 629-14-1), in CD-1 Mice

Ethylene Glycol Diethyl Ether (CAS No. 629-14-1), in New Zealand White Rabbits

Ethylene Glycol Monobutyl Ether (CAS No. 111-76-2), in F/344 Rats

Ethylenediamine (CAS No. 107-15-3), in New Zealand White Rabbits

Ethylene Oxide (CAS No. 75-21-8), in New Zealand White Rabbits

2 Ethylhexanol (CAS No. 104-76-7), in CD-1® Mice

Formamide (CAS No. 75-12-7) Administered by Gavage to Sprague-Dawley (CD®) Rats On Gestational Days 6 Through 19

Formamide (CAS No. 75-12-7) Administered by Gavage to New Zealand White Rabbits On Gestational Days 6 Through 29

Gallium Arsenide (CAS No. 1303-00-0), in Sprague-Dawley (CD) Rats and (CD-1®) Swiss Mice

Gentian Violet (Hexamethyl-p-rosaniline chloride) (CAS No. 548-62-9), in Rats

Gentian Violet (Hexamethyl-p-rosaniline chloride) (CAS No. 548-62-9), in New Zealand White Rabbits

Glyoxal Trimeric Dihydrate (CAS No. 4405-13-4), in Sprague-Dawley (CD®) Rats

Glyoxal Trimeric Dihydrate (CAS No. 4405-13-4), in New Zealand White Rabbits

Goldenseal (Hydrastis canadensis) Root Powder in Swiss (CD-1®) Mice

Goldenseal Root Powder (Hydrastis Canadensis) in the Feed to Sprague-Dawley (CD®) Rats on Gestational Days 6 to 20

Hexachloro-1,3-butadiene, (CAS No. 87-68-3) in Rats

Hydrochlorothiazide, (Cas No. 58-93-5) in Rats

Hydrochlorothiazide (CAS NO. 58-93-5) Administered to CD-1 Mice on Gestational Days 6 Through 15

N-Hexane (CAS No. 110-54-3), in Rats

N-Hexane (CAS No. 110-54-3), in Mice L-5-Hydroxytryptophan (CAS No.4350-09-8), in CD-1 Swiss Mice

L-5-Hydroxytryptophan (CAS No. 4350-09-8), in Sprague-Dawley CD Rats

Isoeugenol (CAS No. 97-54-1), in Sprague-Dawley Rats

Isoprene (CAS No. 78-79-5 ), in Mice and Rats

Isoproterenol Hydrochloride (CAS No. 51-30-9), in CD® Rats

60 Hz Magnetic Fields (EMF) (CAS No. ELECTROMAG), in Rats

Melatonin (CAS No. 73-31-4) Administered by Gavage to Sprague-Dawley (CD®) Rats on Gestational Days 6 through 19

Methacrylamide (CAS No. 79-39-0), in CD-1® Swiss Mice

8-Methoxypsoralen (CAS No. 298-81-7), in New Zealand White Rabbits

8-Methoxypsoralen (CAS 298-81-7), in Sprague-Dawley CD® Rats

a-Methyldopa (CAS No. 555-30-6), in CD Rats

a-Methyldopa (CAS No. 555-30-6), in CD-1® Mice

Methylene Blue Trihydrate (CAS No. 7220-79-3), in Sprague Dawley (CD) Rats

Methylene Blue Trihydrate (CAS No. 7220-79-3), in New Zealand White Rabbits

Methyl Ethyl Ketone (CAS No. 78-93-3), in Mice

N,N'-methylenebisacrylamide (CAS NO. 110-26-9) in Swiss (CD-1¨) Mice

Methyleugenol (CAS No. 93-15-2) in Sprague-Dawley (CD®) Rats

Mono(2-ethylhexyl)phthalate (MEHP) (CAS No. 4376-20-9) in CD-1 Swiss Mice

Naphthalene (CAS No. 91-20-3), in Sprague-Dawley(CD®) Rats

Naphthalene (CAS No. 91-20-3), in New Zealand White Rabbits

Nitrofurazone (CAS No. 59-87-0) Administered to CD-1 Mice on Gestational Days 6 through 15

Nitrofurazone (CAS No. 59-87-0) Administered to New Zealand White Rabbits on Gestational Days 6 through 19

Oxytetracycline Hydrochloride (CAS No. 2058-46-0) in CD® Rats

Oxytetracycline Hydrochloride (CAS No. 2058-46-0), in CD-1® mice

Pesticide/Fertilizer Mixture-California (CAS No. PestFertMix2), in Sprague-Dawley (CD®) Rats

Pesticide/Fertilizer Mixture-Iowa (CAS No. PestFertMix3), in Sprague-Dawley (CD®) Rats

Phenol (CAS No. 108-95-2), in CD® Rats

Phenol (CAS No. 108-95-2), in CD-1® Mice

Polyoxyethylene Sorbitan Monolaurate (TW20) (CAS No. 9005-64-5), in Sprague-Dawley (CD®) Rats

Polyoxyethylene Sorbitan Monooleate (TW80) (CAS No. 9005-65-6), in Sprague-Dawley (CD®) Rats

Scopolamine Hydrobromide (CAS No. 114-49-8), in Rats

Scopolamine Hydrobromide (CAS No. 114-49-8), in Mice

Silver Acetate (CAS No. 563-63-3) in Sprague-Dawley (CD®) Rats

Sodium Chlorate (CAS No. 7775-09-9) in New Zealand White Rabbits

Sodium Flouride (CAS No. 7681-49-4), in Sprague-Dawley (CD®) Rats

Sodium Flouride (CAS No. 7681-49-4), in New Zealand White Rabbits

Sodium Thioglycolate (CAS No. 367-51-1), Administered Topically to New Zealand White Rabbits Gestational Days 6 through 29

Sodium Thioglycolate (CAS No. 367-51-1), Administered Topically to Sprague-Dawley Rats Gestational Days 6 through 19

Alpha-Solanine (CAS No. 20562-02-1) in Swiss (CD-1®) Mice

Sulfamethazine (CAS No. 57-68-1), in CD® Rats

Sulfamethazine (CAS No. 57-68-1), in New Zealand White Rabbits

Sulfamethazine (CAS No. 57-68-1) in F344 Rats

Tetrahydrofuran (CAS No. 109-99-9 ), in Mice and Rats

Thiophenol (CAS No. 108-98-5), in Sprague-Dawley (CD®) Rats

Thiophenol (CAS No. 108-98-5), in New Zealand White Rabbits

Theophylline (CAS No. 58-55-9) Administered to CD®Rats on Gestational Days 6 through 15

1,1,1-Trichloroethane (CAS No. 71-55-6), in CD®Rats [maternal exposure to gd 20]

1,1,1-Trichloroethane (CAS No. 71-55-6), in CD® Rats [maternal exposure to pnd 21]

Triethylene Glycol Dimethyl Ether (CAS No. 112-49-2), in CD-1® Mice

Triethylene Glycol Dimethyl Ether (CAS No. 112-49-2), in New Zealand White Rabbits

Vehicle Studies [Corn Oil (CAS No. 8001-30-7) and Distilled Water] in CD-1 Mice

Vehicle Studies [Corn Oil (CAS No. 8001-30-7) and Distilled Water] in Sprague-Dawley Rats