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Gene Info

Gene Information For:Hs. ABCB4, MRNA 3'-fragment for P-glycoprotein
Sequence ID:NM_018849
NM_000443
NM_018850

Database Links

UniGeneEntrez GeneOMIMSNPViewerAssembliesSNP500CancerRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:7q21.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:7: 86919647 - 86942724

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4837724Full LengthBC042531ATP-binding cassette, sub-family B (MDR/TAP), member 4

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000434  

Protein Infomation

RefSeq

mRNAProteinSwissProtEnzymePfam Motifs
NM_000443 NP_000434 P21439 EC 3.6.3.44 ABC_tran
ABC_membrane
NM_018849 NP_061337 P21439 EC 3.6.3.44  
NM_018850 NP_061338      

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M23234 AAA36207 P21439 EC 3.6.3.44
BC020618 AAH20618 Q6PJ81  
BC042531 AAH42531 Q4G0Q4  
X06181 CAA29547 P21439 EC 3.6.3.44
Z35284 CAA84542 P21439 EC 3.6.3.44

Homologs (from HomoloGene)

Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens ABCB4 NP_061337 R.norvegicus Abcb4 24891   NP_036822 91
M.musculus Abcb4 18670 Gene Info NP_032856 91
A.gambiae AgaP_AGAP005639 1276325   XP_315658 48
D.melanogaster Mdr49 36428   NP_523724 45
A.thaliana PGP21 825388   NP_191774 44
A.thaliana MDR4/PGP4 819314   NP_182223 44
A.thaliana PGP12 839282   NP_171754 43
A.thaliana PGP9 827530   NP_193539 43
A.thaliana PGP5 826974   NP_192092 43
A.thaliana MDR3/PGP3 826951   NP_192091 43
A.thaliana PGP7 834697   NP_199466 43
A.thaliana PGP11 839353   NP_171753 42

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta


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