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X-linked SCID mutation database (IL2RGbase)
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X-linked SCID mutation database (IL2RGbase)
Database of Mutations Causing Human X-Linked SCID
X-linked severe combined immunodeficiency (XSCID or X-SCID)
is an immune disorder caused by mutations in the X-linked gene IL2RG,
which encodes the common gamma chain (![[gamma]](Images/gamma.gif)
c) of the
lymphocyte receptors for interleukin-2 (IL-2) and many other cytokines.
A database of human XSCID mutations (IL2RGbase) has been assembled.
Information on new mutations may be submitted online.
- IL2RGbase: Database of Mutations Causing Human X-Linked SCID
- Distribution of IL2RG mutations causing X-SCID
- Literature citations for the references listed in the mutation data tables
- IL2RGbase data submission form
- List of Investigators
- Other Resources
NIH News Release: Rapid, New Test Developed for Inherited Immune Deficiency
Comments, suggestions and problems to bioinformatics@nhgri.nih.gov
