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Distinguished Scientist Lecture Series

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Series Calendar:
12/15/2008 Dr. Sergei Nedospasov Physiological and Pathogenic Function of Tumor Necrosis Factor and the Consequences of its Blockade in Mice
11/20/2008 Eddy Arnold, Ph.D., Professor HIV-1 Reverse Transcriptase: Structure, Drug Design, and Drug Resistance
11/10/2008 Dr. Lynne Maquat Why mRNA Decay Matters: The Regulation of Hene Expression Through Quality Control and Condition-Dependent Mechanisms
9/22/2008 Dr. Roeland Nusse WNT Signaling and Stem Cell Control
5/2/2008 Dr. Doug Lowy Cervical Cancer Prevention: A New Vaccine for a New Generation
3/5/2008 Laurence H. Hurley, PhD G-quadruplexes: A New Receptor Class for Drug Targeting
1/18/2008 Norbert Perrimon, PhD RNAi Screening in Drosophila: Methods and Applications to Cell Growth, Metabolism, and Cancer Studies
12/14/2007 Jennifer Lippincott-Schwartz, PhD Emerging Fluorescence Technology for the Analysis of Protein Localization and Organelle Dynamics
11/16/2007 Kenneth Offit, MD, MPH Cancer Predisposition Gene Discovery in the Ashkenazim
9/21/2007 Dr. Eric Holland The Biology of Therapeutic Response in Mouse Models of Brain Tumor
5/16/2007 Wayne M. Yokoyama, M.D. Self-Tolerance of Natural Killer Cells: Licensing by MHC Class 1 Molecules
3/21/2007 Eric T. Kool, PhD The Chemistry of Information Transfer in Natural and Designed Genetic Systems
1/19/2007 Gail Martin, PhD FGF Signaling in Vertebrate Embryogenesis: The Importance of Getting it Right
10/25/2006 Andrew McMichael HIV Vaccine Strategies
10/16/2006 Philip Hajduk Protein NMR as a Tool in Drug Discovery and Design
9/15/2006 Dr. James Williamson A Post-Proteomic Approach to Ribosome Assembly
7/20/2006 Avram Hershko, PhD, MD The Ubiquitin System and Some of Its Roles in the Control of Cell Division
5/17/2006 Daniel A. Erlanson, PhD Fragment-Based Drug Discovery at Fluxional Sites in Proteins
3/17/2006 Robert D. Schreiber, PhD Cancer Immunoediting: Fundamental Mechanisms and Therapeutic Implications
2/17/2006 Dr. Judy Lieberman The Silent Treatment: Delivering RNA Interference
1/20/2006 Dr. J. Perren Cobb Injury in the Genomic Era
10/21/2005 Vern L. Schramm, Ph.D. Transition State Analogues and Proliferative DIseases
5/19/2005 J. Michael Bishop, MD Mouse Models for Human Cancer: Authentication and Application
4/15/2005 Dr. Gail E. Sonenshein Novel De Novo NF-kappaB RelB Subunit Activation Pathway and Epithelial to Mesenchymal Transition in Breast Cancer
3/9/2005 Dr. William G. Kaelin, Jr Functions of the von Hippel-Lindau Tumor Suppressor Protein: Insights into O2 Sensing and Cancer
2/18/2005 Mina J.Bissell, PhD The Relation of Tissue Structure to Function and Dysfunction in Normal and Malignant Human Breast: The Role of MMP-3 & ROS
1/28/2005 Dr. Cynthia Wolberger Mechanism and Regulation of Sir2 Deacetylases
10/15/2004 Christopher A. Lipinski, PhD Chemistry-Biology Interactions in Biomedical Research
6/18/2004 Dr. Sarah Spiegel Sphingosine-1-Phosphate: An Enigmatic Signaling Lipid
5/7/2004 Paul F. Barbara, PhD Secondary Structure and Secondary Structure Dynamics of DNA Hairpin Complexes with the Chaperone Protein, HIV-1 Nucleocapsid
4/16/2004 Rudolf Jaenisch, PhD Nuclear Cloning, Stem Cells and Reprogramming of the Genome
3/16/2004 Dr. Helen Piwnica-Worms Cell Cycle-and Checkpoint-Control in Mammals
2/26/2004 Erkki Ruoslahti, MD, PhD Vascular Zipcodes in Tumor Angiogenesis and Metatasis
11/21/2003 Peter E. Wright, PhD Structural Basis for Regulation of Transcription by the General Coactivators CBP/p300: New Paradigms for Molecular Recognition
11/7/2003 Dr. David Livingston Functional Analysis of the BRCA1 Gene Product
6/20/2003 Dr. Peter Jones Awakening Silenced Genes in Human Cancer
6/4/2003 Dr. Gregory Verdine Structural and Mechanistic Studies on Catalytic DNA Binding Proteins
4/29/2003 Steven Rosenberg & Pierre Henkart Immunotherapy in Cancer
2/7/2003 Dr. Sarah Tishkoff Genetic Signatures of Selection in the Human Genome