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A new class of exceptionally effective catalysts that promote the powerful olefin metathesis reaction has been discovered by a team of NIGMS-supported scientists.
With support from NIGMS, scientists from three Chicago-area universities have joined forces to develop new ways of building chemical libraries that will help identify compounds for drug development and basic biomedical research.
NIGMS pledges over $48 million over 5 years to support five Centers of Excellence in Chemical Methodologies and Library Development (CMLD).
NIGMS-funded chemists are using light bulbs to propel organic chemical reactions that are efficient, versatile, and environmentally benign.
NIGMS-supported chemists have discovered an inexpensive, clean and quick way to prepare amines, compounds that are used widely in industry.
The ability to select and develop medicines that act on specific cellular targets has just gained a computational ally — a mathematical algorithm developed by NIGMS-supported researchers that predicts the precise effects a given compound will have on a cell’s molecular components or chemical processes.