Summaries & Associations of Study Results
TR-454 Nickel Sulfate Hexahydrate
Target Organs and Levels of Evidence
NTP Technical Report Number 454
Produced from Chemtrack Database 09/19/01
| CHEMICAL/ CAS NUMBER | PEER REVIEW DATE | PRIMARY USES | ROUTE/EXPOSURE LEVELS | STUDY LABORATORY |
|---|---|---|---|---|
| NICKEL SULFATE HEXAHYDRATE 10101-97-0 |
11/29/94 | NICKEL PLATING. BLACKENING ZINC AND BRASS. MORDANT IN DYEING. (1) | Inhalation R: 0, 0.125, 0.25, OR 0.5 M: 0, .25, .5, OR 1.0 MG/M3; 50/GROUP | Lovelace Inhal Tox Res Inst (DOE) |
| LEVELS OF EVIDENCE OF CARCINOGENICITY--ORGAN/TISSUE (NEOPLASM): | ||||
| MR: NO EVIDENCE | ||||
| NON-NEOPLASTIC LESIONS: | LUNG: CHRONIC ACTIVE INFLAMMATION; MACROPHAGE HYPERPLASIA; ALVEOLAR PROTEINOSIS; FIBROSIS | |||
| LYMPH NODE: (BRONCHIAL) LYMPHOID HYPERPLASIA | ||||
| NASAL CAVITY: OLFACTORY EPITHELIAL ATROPHY | ||||
| FR: NO EVIDENCE | ||||
| NON-NEOPLASTIC LESIONS: | LUNG: CHRONIC ACTIVE INFLAMMATION; MACROPHAGE HYPERPLASIA; ALVEOLAR PROTEINOSIS; FIBROSIS | |||
| LYMPH NODE: (BRONCHIAL) LYMPHOID HYPERPLASIA | ||||
| NASAL CAVITY: OLFACTORY EPITHELIAL ATROPHY | ||||
| MM: NO EVIDENCE | ||||
| NON-NEOPLASTIC LESIONS: | LUNG: CHRONIC ACTIVE INFLAMMATION; BRONCHIALIZATION; MACROPHAGE HYPERPLASIA; INTERSTITIAL INFILTRATION; ALVEOLAR PROTEINOSIS | |||
| LYMPH NODE: (BRONCHIAL) LYMPHOID HYPERPLASIA; MACROPHAGE HYPERPLASIA | ||||
| NASAL CAVITY: OLFACTORY EPITHELIAL ATROPHY | ||||
| FM: NO EVIDENCE | ||||
| NON-NEOPLASTIC LESIONS: | LUNG: CHRONIC ACTIVE INFLAMMATION; BRONCHIALIZATION; MACROPHAGE HYPERPLASIA; INTERSTITIAL INFILTRATION; ALVEOLAR PROTEINOSIS | |||
| LYMPH NODE: (BRONCHIAL) LYMPHOID HYPERPLASIA; MACROPHAGE HYPERPLASIA | ||||
| NASAL CAVITY: OLFACTORY EPITHELIAL ATROPHY | ||||
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